Senior Medical Director, Pulmonary Trials & Equity

Expedition Therapeutics Inc.; San Francisco (CA); On-site; USD 180,000 - 240,000; Full time

Benefits offered by this job

Equity participation

Competitive compensation

Comprehensive benefits package

Job summary

Expedition Therapeutics Inc. in San Francisco seeks a Study Physician | Medical Director to lead medical oversight of pulmonary trials, shaping protocol design, safety monitoring, and data interpretation across early to mid-stage programs.

The ideal candidate is an MD/PhD with industry experience in clinical development, strong cross-functional collaboration, and a track record in regulatory and translational science to drive high-quality study execution.

Qualifications

• MD (or MD/PhD) required.
• 3–5+ years of experience in clinical development within biotechnology or pharmaceutical industry.
• Prior experience as a Study Physician, Medical Monitor, or Medical Director supporting clinical trials.
• Experience in respiratory, pulmonary, immunology, or inflammatory diseases strongly preferred.
• Working knowledge of clinical trial design, GCP, and global regulatory requirements (FDA, EMA).
• Experience supporting Phase 1–3 clinical trials; experience in global studies is a plus.

Responsibilities

• Serve as the medical lead for assigned clinical trials, providing oversight from study concept through execution and reporting.
• Contribute to the design and development of clinical protocols, including endpoints, inclusion/exclusion criteria, and safety monitoring plans.
• Provide ongoing medical monitoring of clinical trials, including review of safety data, adverse events, and protocol deviations.
• Partner closely with Clinical Development, and Clinical Operations to support study execution, site interactions, and CRO oversight.
• Participate in the development of clinical development plans and broader program strategy.
• Collaborate with Regulatory Affairs to support regulatory submissions, briefing documents, and health authority interactions (e.g., FDA, EMA).
• Contribute to the analysis and interpretation of clinical data, including preparation of clinical study reports, abstracts, and publications.
• Work with Translational Medicine and Clinical Pharmacology to incorporate biomarkers, PK|PD, and disease insights into study design and analysis.
• Support pharmacovigilance activities, including safety signal detection and risk management strategies.
• Engage with external stakeholders, including investigators, key opinion leaders (KOLs), and advisory boards.

Skills

Clinical development experience

Regulatory knowledge

Cross-functional collaboration

Data interpretation

Education

MD (or MD/PhD)

Job description

Expedition Therapeutics Inc. in San Francisco seeks a Study Physician | Medical Director to lead medical oversight of pulmonary trials, shaping protocol design, safety monitoring, and data interpretation across early to mid-stage programs.

The ideal candidate is an MD/PhD with industry experience in clinical development, strong cross-functional collaboration, and a track record in regulatory and translational science to drive high-quality study execution.