Senior Medical Director — Oncology Clinical Development

GlaxoSmithKline; Upper Providence (Delaware County); Hybrid; USD 257,000 - 355,000; Full time

Job summary

GlaxoSmithKline is seeking a Medical Director, Oncology Clinical Development - GI. The role is hybrid in Switzerland with on-site expectations and collaboration across locations. You will lead medical monitoring, safety oversight, and data interpretation within complex GI oncology programmes.

Responsibilities include regulatory input, study design support, and cross-functional leadership within the Clinical Matrix Team. Strong clinical trial experience in oncology is essential.

Qualifications

• MD with board certification or eligibility in oncology, haematology, or related specialty.
• Clinical experience in oncology and/or relevant therapeutic areas, with direct exposure to clinical research or drug development.
• Strong knowledge of GCP, ICH guidelines, and global regulatory frameworks.
• Ability to apply clinical judgement to support study design, patient safety, and real-time medical decision-making.

Responsibilities

• Serve as the physician within the clinical programme team, providing medical expertise across study design, conduct, safety oversight, and data interpretation.
• Lead medical monitoring activities for clinical studies, ensuring patient safety, clinical integrity, and compliance with the protocol and regulatory requirements.
• Interpret clinical and safety data from a physician perspective, generating insights that inform study-level and programme-level decisions.
• Partner with the Senior Scientist to ensure medical considerations are integrated into study execution, data generation, and operational delivery.
• Contribute to protocol development, ensuring clinical relevance, patient safety, and feasibility within the CDL framework.
• Provide medical input into regulatory documents and Health Authority interactions, including responses to queries.

Skills

Analytical Thinking

Clinical Data Interpretation

Clinical Development

Clinical Pharmacology

Clinical Trial Designs

Clinical Trials Monitoring

Education

MD or equivalent medical degree

Job description

GlaxoSmithKline is seeking a Medical Director, Oncology Clinical Development - GI. The role is hybrid in Switzerland with on-site expectations and collaboration across locations. You will lead medical monitoring, safety oversight, and data interpretation within complex GI oncology programmes.

Responsibilities include regulatory input, study design support, and cross-functional leadership within the Clinical Matrix Team. Strong clinical trial experience in oncology is essential.