Senior Medical Director, Early Development Oncology

Hydrogen Group; Boston (MA); On-site; USD 250,000 - 360,000; Full time

Job summary

Hydrogen Group in Boston, MA, is seeking a Senior Medical Director for Early Development Oncology to lead global clinical development across solid tumor programs, guiding assets from preclinical through early-phase studies. Boston relocation support is offered.

The role requires an MD with board certification in Oncology/Hematology, 5+ years in clinical oncology, and proven biopharma leadership. Fluency in English is essential, with additional languages a plus.

Qualifications

• MD with board certification in Oncology/Hematology or related specialty.
• 5+ years of clinical oncology patient care experience.
• 5+ years in biopharma, including early-stage drug development.
• Experience engaging with global regulatory authorities.
• Strong leadership with the ability to influence across matrix teams.
• Fluent in English; additional European languages are a plus.

Responsibilities

• Act as the medical lead and primary clinical representative for early-stage oncology programs
• Establish the clinical development vision for assets entering the pipeline
• Design and execute clinical strategies spanning preclinical through Phase I/II
• Provide oversight on medical safety, study design, and benefit–risk evaluation
• Guide preclinical activities to support clear, clinically grounded decision-making
• Lead interactions with key opinion leaders, academic partners, and regulatory authorities
• Identify and leverage external collaborations to strengthen development programs
• Lead cross-functional teams to deliver aligned, high-quality outcomes
• Foster accountability, pace, and ownership across initiatives

Skills

Leadership

Strategic thinking

Delivery-focused

Cross-functional collaboration

Education

MD with board certification in Oncology, Hematology, or related specialty

Job description

Title: Senior Medical Director, Early Development Oncology

Location: Boston, MA (Relocation support offered)

Own the clinical strategy of next-generation Oncology assets from day one. We’re partnered with a global pharma to hire a new Senior Medical Director, Early Development Oncology, to lead global clinical development across solid tumor programs, shaping assets from preclinical through early-phase studies

Key Responsibilities

• Act as the medical lead and primary clinical representative for early-stage oncology programs
• Establish the clinical development vision for assets entering the pipeline
• Design and execute clinical strategies spanning preclinical through Phase I/II
• Provide oversight on medical safety, study design, and benefit–risk evaluation
• Guide preclinical activities to support clear, clinically grounded decision-making
• Lead interactions with key opinion leaders, academic partners, and regulatory authorities
• Identify and leverage external collaborations to strengthen development programs
• Lead cross-functional teams to deliver aligned, high-quality outcomes
• Foster accountability, pace, and ownership across initiatives

Requirements

• M.D. with board certification (or international equivalent) in Oncology, Hematology, or a related specialty
• 5+ years of clinical experience in oncology patient care
• 5+ years of biopharma industry experience, including early-stage drug development
• Solid understanding of oncology R&D across diverse modalities
• Experience contributing to or leading early-phase clinical trials
• Background in translational and/or clinical research (peer-reviewed publications a plus)
• Experience engaging with global regulatory authorities
• Strong leadership skills with the ability to influence across matrix teams
• Strategic thinker with a hands-on, delivery-focused mindset
• Fluent in English (additional European languages beneficial)