Senior Medical Director, Clinical Development (Rheumatology)

Avalo Therapeutics; Chesterbrook (PA); On-site; USD 250,000 - 360,000; Full time

Job summary

Avalo Therapeutics is seeking a Medical Director to guide clinical development from early trials through regulatory approval, focusing on rheumatoid and immune-mediated inflammatory diseases. You will coordinate with operations, regulatory, biomarker teams, and CROs to ensure efficient trial execution in a fast-paced environment.

Ideal candidates have 5+ years in biotech/pharma development, with direct experience in phase 2/3 studies and a background in biologics.

Qualifications

• MD or equivalent medical degree required.
• Minimum 5+ years of biotech/pharma/clinical development experience.
• Direct experience leading late-stage (2/3) drug development.
• Experience with biologics desirable.
• Strong understanding of early development, dose escalation, safety monitoring.

Responsibilities

• Provide medical leadership for assigned clinical program(s).
• Contribute to early clinical development strategy including dose selection and trial design.
• Support design and regulatory documents in compliance with GCP and GMP.
• Serve as Medical Monitor for ongoing studies and review safety data.
• Collaborate with CROs and external vendors to ensure high-quality study execution.
• Prepare medical writing for study reports and labeling.

Skills

Medical leadership

Clinical development strategy

Regulatory submissions

Safety monitoring

Biomarker strategy

Education

MD or equivalent medical degree

Tools

ICH-GCP familiarity

Job description

Avalo Therapeutics is seeking a Medical Director to guide clinical development from early trials through regulatory approval, focusing on rheumatoid and immune-mediated inflammatory diseases. You will coordinate with operations, regulatory, biomarker teams, and CROs to ensure efficient trial execution in a fast-paced environment.

Ideal candidates have 5+ years in biotech/pharma development, with direct experience in phase 2/3 studies and a background in biologics.