Senior Media Development Scientist – High-Throughput

Vertex Pharmaceuticals LLC; Boston (MA); On-site; USD 74,000 - 111,000; Full time

Job summary

Vertex Pharmaceuticals LLC is seeking a lab-based Senior Scientific Associate, Media Development to expand high-throughput media development capabilities and accelerate optimization of stem cell-based cell therapy processes. The role uses DoE-based screening on 96-well plates and Ambr platforms, with automation, data analytics, and PAT to identify key drivers of performance.

You will work with scientists and cross-functional teams to build robust media formulations, improve workflows, and scale

Qualifications

• Bachelor's degree in Biology, Chemical Engineering, Biomedical Engineering, Biotechnology, Biochemistry, or related field.
• Bachelor's degree and 2+ years of relevant experience, or a Master's degree and 0-2 years of relevant experience.
• Experience in cell culture, bioprocess development, media development, high-throughput experimentation, or quantitative analysis of biological data.
• DoE, stem cell culture, small-scale bioreactors, laboratory automation, PAT, or high-throughput screening is preferred.

Responsibilities

• Executes high-throughput and DoE-based media screening studies using 96-well plate, ambr15, ambr250, and other scalable cell culture platforms
• Partners with scientists to evaluate main effects and interactions among media components, concentrations, and culture conditions
• Establishes and improves screening workflows to increase throughput, consistency, and speed
• Applies statistical and data analytics to large datasets to identify key drivers and support media optimization decisions
• Integrates cell culture, process, PAT, and analytical data with cross-functional partners to build process understanding and translate findings
• Implements automated/semi-automated workflows for liquid handling, sampling, cell counting, and sample processing
• Operates and troubleshoots cell culture, bioreactor, automation, and analytical platforms
• Maintains high-quality documentation and contributes to protocols and reports
• Drives continuous improvement of experimental platforms and workflows to expand screening capability

Skills

DoE screening

Data analysis

Laboratory automation

Cross-functional collaboration

Education

Bachelor's degree in Biology or engineering

Bachelor's + 2+ years or Master’s +0-2 years

Tools

Ambr platforms

96-well plate workflows

Job description

Vertex Pharmaceuticals LLC is seeking a lab-based Senior Scientific Associate, Media Development to expand high-throughput media development capabilities and accelerate optimization of stem cell-based cell therapy processes. The role uses DoE-based screening on 96-well plates and Ambr platforms, with automation, data analytics, and PAT to identify key drivers of performance.

You will work with scientists and cross-functional teams to build robust media formulations, improve workflows, and scale