Senior Manager, Portfolio Analytics & Strategy

Scorpion Therapeutics; United States; On-site; USD 170,000 - 210,000; Full time

Job summary

Scorpion Therapeutics seeks a Senior Manager, Portfolio Analytics & Strategy to lead portfolio analysis, benchmarking, and PTRS across the R&D portfolio. You will partner with product teams and governance bodies to translate development risk into decision-ready options.

The role requires advanced training in decision analysis and probabilistic modeling, with experience facilitating PTRS assessments and end-to-end drug development knowledge. AI-enabled tools are encouraged to drive insights.

Qualifications

• Doctorate + 2 years OR Master’s + 4 years OR Bachelor’s + 6 years OR Associate’s + 10 years OR High school/GED + 12 years in R&D portfolio management/analytics/life sciences/management consulting/decision analysis.

Responsibilities

• Lead portfolio analysis, performance tracking, and benchmarking across R&D portfolio.
• Own PTRS methodology, standards, guardrails, governance cadence, and documentation.
• Develop PTRS tools, dashboards, and evidence workflows for decision support.

Skills

PTRS process

Decision analysis

Monte Carlo

Risk modeling

AI-enabled tools

Executive communication

Education

PhD or Master’s or Bachelor’s or Associate’s or HS/GED in relevant field

Tools

AI-enabled tools

Job description

Senior Manager, Portfolio Analytics & Strategy

What You Will Do

• Lead portfolio analysis, performance tracking, and benchmarking; own Amgen’s Probability of Technical and Regulatory Success (PTRS) process across the R&D portfolio.
• Serve as a strategic thought partner to Product Teams, Therapeutic Area, and Portfolio Governance by translating development risks, evidence, and uncertainty into decision-ready options.
• Oversee technology initiatives that enable PTRS and broader portfolio decision support.

Key Responsibilities

• Lead and facilitate enterprise PTRS assessments at key development, investment, and governance milestones.
• Own and continuously evolve PTRS methodology, standards/benchmarks/guardrails, governance cadence, and documentation (including integration with portfolio and business-case processes).
• Develop PTRS and risk‑assessment tools (data products, evidence workflows, dashboards, decision-support capabilities).
• Partner with Product Teams to assess risk across target product profiles, indication/population choices, biomarker strategies, and clinical development options.
• Support portfolio reviews, prioritization, and investment decisions; track performance and participate in industry benchmarking across KPIs.
• Deliver decision‑ready insights and calibrate assessments using historical outcomes and internal/external benchmarks.

What We Expect Of You

Basic Qualifications

• Doctorate + 2 years OR Master’s + 4 years OR Bachelor’s + 6 years OR Associate’s + 10 years OR High school/GED + 12 years in R&D portfolio management/analytics/life sciences/management consulting/decision analysis.

Preferred Qualifications

• Advanced degree; 5+ years experience; decision analysis & probabilistic modeling (decision trees, Monte Carlo, risk modeling).
• Experience facilitating PTRS/PoS comparable assessments.
• Deep end-to-end drug development knowledge (scientific, clinical, regulatory, CMC, operational, competitive).
• Comfort with AI-enabled tools; strong analytical/strategic thinking; executive communication; thrives in fast-paced, ambiguous, matrixed environments.