Senior Manager MES / Manufacturing Transformation | m/w/d

United States Digital Space LLC; United States; Hybrid; USD 150,000 - 210,000; Full time

Benefits offered by this job

Flexible working model

Remote work options

30 vacation days+

Job summary

United States Digital Space LLC is seeking a consulting leader to take end-to-end ownership of international MES and Manufacturing Transformation programs across multiple sites. You will coordinate business, IT, Quality, sites, vendors, and system integrators to ensure successful delivery through design, rollout, and stabilization.

You will shape governance, manage scope, budget, risks, and dependencies, and drive validation and regulatory alignment (GxP) in complex, global projects.

Qualifications

• Consulting experience in leading complex international programs in life sciences/pharma.
• Strong knowledge of MES and Manufacturing IT and hands-on implementation experience.
• Experience with Quality, Automation/OT, ERP/SAP interfaces and multi-site rollout.

Responsibilities

• Take end-to-end ownership of international MES and Manufacturing Transformation programs across multi-site implementations.
• Lead governance, solution design, and rollout through go-live and stabilization.
• Coordinate with business, IT, Quality, sites, vendors and system integrators to ensure delivery.

Skills

MES

ERP/SAP

Manufacturing IT

GxP & CSV

English proficiency

German proficiency

International travel

Tools

MES

ERP

Job description

Your missionYou’re a team player, authentic, open, and face challenges with a positive mindset? Then you’re a perfect fit for us!

• Take end-to-end ownership of international MES and Manufacturing Transformation programs – from program setup, governance, solution design, and implementation through to rollout, go-live, and stabilization – while keeping scope, roadmap, budget, resources, risks, and dependencies firmly under control. Across complex multi-site programs, you bring together business functions, IT, Quality, sites, vendors, and system integrators, providing clear direction to project teams throughout demanding and critical phases. Functional projects and workstreams covering process optimization and harmonization, solution design, system integration, data flows, and data migration are managed with confidence, while validation activities can also be supported conceptually at both program and project level. With a comprehensive understanding of the relevant functional and technical concepts, you identify dependencies early and work closely with experts to develop and evaluate robust solutions. Particularly during rollout, readiness, and go-live phases, you drive decisions and follow them through, ensure successful delivery, manage escalations, and represent the program confidently towards management, steering committees, and other relevant stakeholders.

Your profile Consulting experience in leading complex international programs and projects within the life sciences or pharmaceutical industry forms the foundation of your expertise. Strong knowledge of MES and Manufacturing IT is complemented by hands‑on experience in the implementation, integration, and multi‑site rollout of corresponding solutions. Pharmaceutical manufacturing processes and their interfaces with Quality, Automation/OT, ERP/SAP, and other relevant systems are areas in which you are highly confident. A solid understanding of GxP, Computerized Systems Validation, and pharmaceutical Quality processes enables you to translate regulatory requirements effectively into program planning, governance, and delivery. Excellent German and English skills, combined with a willingness to travel internationally, enable you to operate confidently across complex global program environments.

Your start with usAt our company, you’ll find a work environment where initiative, collaboration, and mutual support are truly valued. You can expect exciting projects, a fair salary, plenty of development opportunities, and a flexible working model tailored to your needs.Your journey with us starts with a well‑structured onboarding, including two welcome days at our Frankfurt office, a buddy program, and access to internal networks to help you feel at home from day one. We offer full flexibility with flexible working hours, remote work options, and even the chance to work temporarily from abroad. With 30 vacation days plus additional paid leave for special occasions, as well as a time value account for extended breaks like sabbaticals, we ensure you have the space to recharge and balance life and work. Our internal training curriculum, additional learning formats, and tailored development paths support your individual career goals. Regular events, cross‑location networks, and our feedback platform miaX create space for exchange, ideas, and collaboration. We support your well‑being with a subsidized Urban Sports Club membership and exclusive perks through our Corporate Benefits platform. You can also privately use your company IT equipment, and stay mobile with flexible options like JobRad, a company car, or a BahnCard. And because we value your network, we reward successful referrals with an attractive bonus. We work in ahybridmodel: depending on the project requirements, you will workremotely, in one of our offices or directly at the customer's premises.