Senior Manager, Chemical Development & CMO Partnerships

Maze Therapeutics; South San Francisco (CA); Hybride; USD 158 000 - 193 000; Plein temps

Avantages offerts par ce poste

Equity incentive plan

401(k) with employer match

Medical, dental, vision insurance

Résumé du poste

Maze Therapeutics seeks a Manager, Chemical Development to lead external CMOs in the manufacture and testing of drug substance and starting materials. You will work with discovery teams to move candidates toward clinical supply, ensuring cGMP compliance and regulatory alignment.

You will own process optimization, scale-up strategies, and cross-functional collaborations with QA/regulatory teams to keep timelines and quality on track. Travel to domestic and international sites is expected.

Qualifications

• MS or PhD in synthetic organic chemistry with process chemistry experience and cGMP manufacturing exposure.
• Experience with process optimization and scale-up in chemical manufacturing.
• Familiarity with cGMP regulatory compliance in chemical manufacturing.
• Ability to prepare technical reports and present findings to cross-functional teams.

Responsabilités

• Direct international CMOs developing new chemical processes and troubleshoot manufacturing issues.
• Analyze production methods and recommend improvements to support timelines.
• Partner with QA and Regulatory to ensure audit readiness and compliance.
• Prepare technical reports and present results to internal teams and external partners.
• Track industry trends to improve manufacturing processes.

Connaissances

Synthetic organic chemistry

Process chemistry

cGMP compliance

Technical reporting

ChemDraw

SciFinder

Project management

Travel readiness

Formation

MS or PhD in synthetic organic chemistry

Outils

ChemDraw

SciFinder

Description du poste

Maze Therapeutics seeks a Manager, Chemical Development to lead external CMOs in the manufacture and testing of drug substance and starting materials. You will work with discovery teams to move candidates toward clinical supply, ensuring cGMP compliance and regulatory alignment.

You will own process optimization, scale-up strategies, and cross-functional collaborations with QA/regulatory teams to keep timelines and quality on track. Travel to domestic and international sites is expected.