Senior IT Program Leader — Multi-Portfolio PMO (Irvine)

FUJIFILM Biosciences; Irvine (CA); On-site; USD 126,900 - 145,000; Full time

Benefits offered by this job

Medical Insurance

Dental Insurance

Vision Insurance

401k

Paid Time Off

Job summary

FUJIFILM Biosciences in Irvine, CA is hiring a Senior IT Project Manager to direct large, complex IT programs and oversee portfolio execution within LSS-IT. This on-site role drives program management, comprehensive financial management, and executive-level portfolio status reporting.

The Senior IT Project Manager actively matures PMO capabilities and manages cross-project dependencies to ensure strategic enterprise alignment and value realization.

Qualifications

• Bachelor’s degree in information technology, business administration, or a related field.
• 8+ years of IT project and program management experience.
• Proven experience managing multi-million-dollar technology portfolios and complex enterprise deployments.
• Strong capability in portfolio-level financial management, budget forecasting, and executive status reporting.
• Advanced vendor management and contract negotiation skills.
• PMP, PgMP, or advanced Agile certification.
• Experience operating within GxP-regulated environments (21 CFR Part 11, EU Annex 11).
• Deep expertise in establishing and scaling IT PMO functions and portfolio dashboards.
• Ability to speak, read, and write in English.
• Good verbal and written communication skills; effective presentation skills

Responsibilities

• Direct multi-track, high-budget IT projects and programs through the full execution lifecycle.
• Drive comprehensive financial management at the project level, including CAPEX/OPEX forecasting, variance analysis, and monitoring funding burn rates.
• Manage master program schedules, risk mitigation strategies, and complex cross-project dependencies.
• Lead large-scale vendor engagements, complex SOW negotiations, and deliverable acceptance.
• Oversee complex cutover planning and execute structured hypercare support models.
• Manage financial health across the IT portfolio, tracking total spend against approved budgets and reconciling project costs.
• Lead executive status reporting, maintaining comprehensive portfolio dashboards that track program health, execution risks, and financial metrics.
• Manage execution capacity and coordinate resource allocation adjustments across active programs.
• Partner with IT Business Partners to monitor ROI and drive value realization tracking post-deployment.
• Present project health updates, budget variances, and funding adjustment requests to the IT Steering Committee (SteerCo).
• Ensure enterprise projects maintain Governance Architecture Review Board (GARB) alignment during design and build.
• Develop and mature PMO frameworks, project execution templates, and financial tracking metrics.
• Enforce the Two-Speed IT operational model for active projects, managing compliance, risk, and architecture requirements during execution.

Skills

Project management

Portfolio management

Budget forecasting

Vendor management

Executive reporting

English proficiency

GxP compliance

PMO scaling

Governance

Stakeholder communication

Education

Bachelor's degree in information technology or business

PMP/PgMP or advanced Agile certification

Job description

FUJIFILM Biosciences in Irvine, CA is hiring a Senior IT Project Manager to direct large, complex IT programs and oversee portfolio execution within LSS-IT. This on-site role drives program management, comprehensive financial management, and executive-level portfolio status reporting.

The Senior IT Project Manager actively matures PMO capabilities and manages cross-project dependencies to ensure strategic enterprise alignment and value realization.