Senior IHC/ISH Validation Specialist

Labcorp; Torrance (CA); On-site; USD 34,000 - 55,000; Full time

Benefits offered by this job

Medical, Dental, Vision

401(k)

PTO / FTO

Tuition Reimbursement

Employee Stock Purchase Plan

Job summary

Labcorp is seeking an Advanced Staining Assay Validation Specialist to join our Torrance, CA team. The role focuses on validation, verification, and development of advanced staining assays such as IHC, ISH, and FISH, with preference for Histotechnologist experience.

The position supports validation projects from planning through testing to reporting, ensuring compliance with GxP, CAP, and CLIA standards. Strong data analysis and documentation skills are required.

Qualifications

• High School Diploma.
• One year experience in laboratory assay validation or related work within a histology lab.
• One year histology exposure.

Responsibilities

• Execute immunohistochemistry (IHC) and in-situ hybridization (ISH) assay validation and verification experiments and other methods as applicable.
• Demonstrate working knowledge of department specific instruments (such as IHC/ISH autostainers) and equipment.
• Support development and writing of validation plans, reports, SOPs, pathology report forms, and study setup forms.
• Perform data analysis and documentation.
• Prepare client-facing materials.
• Maintain and organize validation documentation.
• Organize and scan slides as required according to protocols.
• Regularly provide status update and report to the Staff and/or Lead scientists.
• Act as a liaison between scientific side and lab staff to train and communicate new methods to the clinical testing staff.
• Perform validation-related testing, screenings, and proficiency testing.
• Execute preparingsamples incl.decalcification, processing, embedding, microtomy, and re-embedding of human commercial tissue specimens for validation.
• Perform routine, special stains, and advanced staining (e.g.IHC, ISH, FISH) assays and other techniques according to SOPs, protocols, and in line with global and regional regulatory requirements.
• Utilize knowledge and experience with histology samples to maintain proper storage conditions and facilitate labelling of commercial/validation blocks and slides (stained and unstained).
• Adheres to lab safety policies and universal precaution guidelines at all times.
• Maintains clean workspaces.
• Operate, maintain, and troubleshoot lab instruments.
• Perform QC checks and manage vendor interactions.
• Inform management and lab operations about instrument issues and handle service requests.
• Work with scientists and operations globally.
• Ensure consistent approach to validation of assays.
• Proactively support training and seek process improvements.

Skills

IHC

ISH

FISH

Histology

Assay validation

Data analysis

SOPs

Education

Associate’s Degree in Chemical or Biological science

High School Diploma

Tools

IHC autostainers

ISH autostainers

Laboratory instruments

Excel

Word

Job description

Labcorp is seeking an Advanced Staining Assay Validation Specialist to join our Torrance, CA team. The role focuses on validation, verification, and development of advanced staining assays such as IHC, ISH, and FISH, with preference for Histotechnologist experience.

The position supports validation projects from planning through testing to reporting, ensuring compliance with GxP, CAP, and CLIA standards. Strong data analysis and documentation skills are required.