Senior HVAC Maintenance Technician

AstraZeneca GmbH; Santa Monica (CA); On-site; USD 72,000 - 108,000; Full time

Benefits offered by this job

Short-term incentive bonuses

Equity-based awards for salaried roles

Health, dental, and vision coverage

Paid time off

Job summary

AstraZeneca GmbH in Santa Monica seeks an experienced HVAC/Facilities engineer to lead maintenance of critical pharma systems in GMP spaces. You will ensure cleanroom ISO 14644 compliance, manage BMS/EMS/SCADA tuning, and drive validation activities (IQ/OQ/PQ) with strong CAPA and documentation discipline.

The role requires 6–10+ years in regulated environments, cleanroom HVAC expertise, and proficiency with PID control, alarms, and validation practices.

Qualifications

• 6–10+ years in HVAC maintenance in pharma/biotech or GMP environments
• Cleanroom HVAC experience is essential
• GMP knowledge: ISO cleanroom classifications, airflow visualization, pressurization cascades
• Validation: IQ/OQ/PQ, GDP, Change Control
• Diagnostics: calibration, vibration, thermography; data integrity

Responsibilities

• Lead maintenance across AHUs, chillers, boilers, and other systems in GMP spaces
• Ensure ISO cleanroom compliance and support aseptic areas
• Tune PID loops and manage alarms in BMS/EMS/SCADA
• Coordinate calibration and support IQ/OQ/PQ with validation docs
• Drive CAPA investigations using RCA methods
• Audit readiness for FDA/EU GMP and maintain validated state
• Plan outages and capital projects with contractors
• Mentor junior technicians and promote safety culture

Skills

HVAC maintenance

GMP knowledge

BMS/EMS/SCADA

Validation & IQ/OQ/PQ

Root cause analysis

Safety leadership

Documentation

Education

High school diploma/GED

Bachelor’s in Mechanical/Building

Tools

Siemens

Allen-Bradley

Johnson Controls

Job description

What you’ll do

• Lead preventive/predictive/corrective maintenance across AHUs, chillers, boilers, heat exchangers, VAVs, exhaust, dehumidifiers, and split systems—owning temperature, humidity, airflow, and pressurization in GMP spaces.
• Ensure cleanroom compliance with ISO 14644: HEPA integrity, airflow patterns, recovery times, and differential pressures; support aseptic areas and gowning zones.
• Optimize and troubleshoot BMS/EMS/SCADA (Siemens, Allen-Bradley, Johnson Controls): tune PID loops, rationalize alarms, adjust sequences of operation, and document via change control.
• Coordinate calibration (temperature, RH, pressure, flow) and support IQ/OQ/PQ with solid validation documentation.
• Drive investigations and CAPA using RCA methods (5-Why, Fishbone) and maintain impeccable cGMP/GDP records and SOPs.
• Champion audit readiness (FDA/EU GMP) and keep systems in a validated state.
• Improve energy and performance: VFDs, heat recovery, demand-based ventilation, and smart control strategies.
• Plan and execute outages/turnarounds/capital projects with contractors, materials, and risk assessments.
• Lead safety culture (LOTO, confined space, hot work, arc-flash; EPA 608 refrigerants) and mentor junior techs.
• Manage spares and CMMS workflows; partner closely with Quality, Manufacturing, Engineering, Validation, and Operations.
• Impact that matters: Your work directly supports compliant manufacturing and product quality.
• Variety and ownership: Complex systems, cross-functional collaboration, and continuous improvement.
• Growth and mentorship: Be the SME and coach for a high-performing team.

Minimum Requirements:

• High school diploma/GED
• 6–10+ years in HVAC maintenance, including 3–5 years in pharma/biotech or regulated GMP environments
• Cleanroom HVAC experience is essential.
• GMP know‑how: ISO cleanroom classifications, airflow visualization/smoke studies, pressurization cascades, aseptic requirements.
• Technical strengths: AHUs/chillers/boilers/hydronics, humidity control, HEPA; strong controls/BMS proficiency (PID, trends, data integrity).
• Validation: Sensor calibration, IQ/OQ/PQ, GDP, CAPA, Change Control.
• Diagnostics: Advanced troubleshooting, basics of vibration analysis and thermography; instrumentation (anemometers, micromanometers, particle counters, data loggers).
• Soft skills: Clear communication, teamwork, stakeholder management, decisive under time pressure, meticulous documentation.
• Physical: Lift 50 lbs, ladders/heights/mechanical spaces, PPE for labs/cleanrooms, after-hours/on-call rotation.

Desired:

• Technical diploma/apprenticeship in HVAC/Mechanical/Building Services;
• Bachelor’s in Mechanical/Building is a plus.
• Certifications: Safety training preferred; manufacturer training on chillers/controls and GxP/cleanroom courses are a plus.

The annual base pay (or hourly rate of compensation) for this position ranges from $71,749.60 - 107,624.40. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

Date Posted

04-Aug-2026

Closing Date

21-Aug-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.