Senior HVAC Maintenance Technician

AstraZeneca GmbH; Los Angeles (CA); On-site; USD 72,000 - 108,000; Full time

Benefits offered by this job

Health insurance

Dental plan

Vision coverage

Retirement plan

Paid time off

Job summary

AstraZeneca GmbH in Los Angeles seeks an experienced HVAC/Facilities technician for GMP environments. You will lead maintenance across AHUs, chillers, boilers, heat exchangers and cleanroom systems, ensuring ISO cleanroom integrity and regulatory compliance.

The role emphasizes BMS/SCADA optimization, calibration, validation support, and CAPA investigations, with focus on safety and continuous improvement. Ideal candidates have 6–10+ years in pharma HVAC, strong controls/BMS skills (PID,

Qualifications

• 6–10+ years in HVAC maintenance with 3–5 years in pharma/biotech or GMP environments.
• Cleanroom HVAC experience is essential.
• Strong controls/BMS proficiency (PID, trends, data integrity).
• GMP know‑how: ISO cleanroom classifications, airflow visualization/smoke studies, pressurization cascades.
• Validation: IQ/OQ/PQ, GDP, CAPA, Change Control.

Responsibilities

• Lead preventive/predictive/corrective maintenance across HVAC systems in GMP spaces.
• Ensure ISO cleanroom compliance and support aseptic areas.
• Tune PID loops, rationalize alarms, adjust sequences of operation, document changes.
• Coordinate calibration and support IQ/OQ/PQ with validation docs.
• Drive CAPA investigations using RCA methods and maintain cGMP records.
• Champion audit readiness and keep systems validated.

Skills

HVAC maintenance

GMP experience

BMS/EMS/SCADA

Calibration & validation

ISO 14644

Root cause analysis

Safety training

Education

Technical diploma or apprenticeship in HVAC

Bachelor's in Mechanical/Building Services

Tools

Siemens controls

Allen-Bradley PLC

Johnson Controls Metasys

Job description

What you’ll do

• Lead preventive/predictive/corrective maintenance across AHUs, chillers, boilers, heat exchangers, VAVs, exhaust, dehumidifiers, and split systems—owning temperature, humidity, airflow, and pressurization in GMP spaces.
• Ensure cleanroom compliance with ISO 14644: HEPA integrity, airflow patterns, recovery times, and differential pressures; support aseptic areas and gowning zones.
• Optimize and troubleshoot BMS/EMS/SCADA (Siemens, Allen-Bradley, Johnson Controls): tune PID loops, rationalize alarms, adjust sequences of operation, and document via change control.
• Coordinate calibration (temperature, RH, pressure, flow) and support IQ/OQ/PQ with solid validation documentation.
• Drive investigations and CAPA using RCA methods (5-Why, Fishbone) and maintain impeccable cGMP/GDP records and SOPs.
• Champion audit readiness (FDA/EU GMP) and keep systems in a validated state.
• Improve energy and performance: VFDs, heat recovery, demand-based ventilation, and smart control strategies.
• Plan and execute outages/turnarounds/capital projects with contractors, materials, and risk assessments.
• Lead safety culture (LOTO, confined space, hot work, arc-flash; EPA 608 refrigerants) and mentor junior techs.
• Manage spares and CMMS workflows; partner closely with Quality, Manufacturing, Engineering, Validation, and Operations.

What you’ll bring

• Education: Technical diploma/apprenticeship in HVAC/Mechanical/Building Services; bachelor’s in Mechanical/Building is a plus.
• Experience: 6–10+ years in HVAC maintenance, including 3–5 years in pharma/biotech or regulated GMP environments; cleanroom HVAC experience is essential.
• Technical strengths: AHUs/chillers/boilers/hydronics, humidity control, HEPA; strong controls/BMS proficiency (PID, trends, data integrity).
• GMP know‑how: ISO cleanroom classifications, airflow visualization/smoke studies, pressurization cascades, aseptic requirements.
• Validation: Sensor calibration, IQ/OQ/PQ, GDP, CAPA, Change Control.
• Diagnostics: Advanced troubleshooting, basics of vibration analysis and thermography; instrumentation (anemometers, micromanometers, particle counters, data loggers).
• Certifications: Safety training preferred; manufacturer training on chillers/controls and GxP/cleanroom courses are a plus.
• Soft skills: Clear communication, teamwork, stakeholder management, decisive under time pressure, meticulous documentation.
• Physical: Lift 50 lbs, ladders/heights/mechanical spaces, PPE for labs/cleanrooms, after-hours/on-call rotation.

Why this role

• Impact that matters: Your work directly supports compliant manufacturing and product quality.
• Variety and ownership: Complex systems, cross-functional collaboration, and continuous improvement.
• Growth and mentorship: Be the SME and coach for a high-performing team.

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

The annual base pay (or hourly rate of compensation) for this position ranges from $71,749.60 - 107,624.40 . Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

Date Posted

07-Aug-2026

Closing Date

27-Aug-2026