Senior HPC Infrastructure Engineer

Guardant Health; Palo Alto (CA); Hybrid; USD 173,000 - 238,000; Full time

Benefits offered by this job

Hybrid work model

Job summary

Guardant Health is seeking a Staff HPC Engineer in Palo Alto to lead and scale high-performance compute environments. You will manage multiple HPC clusters, integrate cloud bursting, and troubleshoot the production stack from shell scripts to code, while collaborating with networking, storage, and MSP teams.

The role requires 8–12 years of systems engineering experience, deep Linux knowledge, and hands-on work with Slurm, Kubernetes, GPFS, and cloud platforms.

Qualifications

• Bachelor’s degree in Computer Science or a related field with 8–12 years of relevant experience; Master’s degree with 6–8 years; or PhD with 3–5 years.
• Hands-on experience with Linux/Unix administration and TCP/IP networking.
• Experience with automation tools such as Ansible or equivalent technologies.
• Experience with high-performance networking technologies (InfiniBand, RoCE, RDMA).
• Experience supporting large-scale HPC/compute environments and on-premise and cloud infrastructure.

Responsibilities

• Manage multiple HPC clusters and cluster file systems.
• Integrate cloud bursting as part of HPC abstraction work.
• Troubleshoot production stack to source code level.
• Maintain and monitor infrastructure and tooling.
• Support remote locations, including international sites.
• Mentor junior engineers on HPC best practices.

Skills

Linux administration

HPC

Networking

Slurm

Kubernetes

Storage

Ansible

AWS

Education

Bachelor’s degree in Computer Science

Master’s degree in Computer Science

PhD

Tools

Slurm

GPFS

Warewulf

Ansible

Kubernetes

AWS

GCP

Job description

Guardant Health is seeking a Staff HPC Engineer in Palo Alto to lead and scale high-performance compute environments. You will manage multiple HPC clusters, integrate cloud bursting, and troubleshoot the production stack from shell scripts to code, while collaborating with networking, storage, and MSP teams.

The role requires 8–12 years of systems engineering experience, deep Linux knowledge, and hands-on work with Slurm, Kubernetes, GPFS, and cloud platforms.