Senior Director, US Oncology Operations & GMASE Lead

GSK; Durham (NC); On-site; USD 210,000 - 260,000; Full time

Job summary

GSK is seeking a Sr Director, Global Monitoring & Site Engagement (GMASE), US Oncology Head to accelerate US Oncology trial delivery and broaden patient access, including non-traditional and community-based settings. This leader will drive continuous evidence generation and partner across Clinical, Medical, Regulatory, and DS&M to ensure high-quality, timely trial outcomes.

The role demands extensive oncology trial leadership, deep therapeutic insight, and a track record of executing complex,

Qualifications

• Bachelor’s degree in life sciences, healthcare, business or a related field, or equivalent experience.
• Minimum of 10 years of pharmaceutical R&D or related industry experience.
• Extensive (8+ years) leadership experience in clinical operations within the relevant therapeutic area.
• Deep therapeutic area expertise and understanding of Oncology strategy, data, operational needs, and commercial positioning to enable aligned execution.
• Experience owning end-to-end execution outcomes at portfolio or TA level, including accountability for delivery tradeoffs, risk resolution, and performance.

Responsibilities

• Accelerate delivery and increase the percentage of US patients enrolled in Oncology studies across all development phases.
• Champion continuous evidence generation — embedding real-time data capture and evidence approaches throughout the trial lifecycle.
• Lead non-traditional site strategies, including community-based and decentralized settings.
• Represent GSK at conferences and with external stakeholders, building trust through expertise and leadership.
• Provide senior leadership and people management for US Oncology Clinical Operations teams.
• Partner with Clinical, Medical, Regulatory, and other Development Operations functions to drive integrated delivery.
• Translate R&D and strategy into executable country-level plans aligned to portfolio needs.
• Provide clinical monitoring oversight, including studies executed by strategic partners and CROs.
• Maintain understanding of the US oncology healthcare environment, regulatory landscape, and patient access dynamics.
• Own operational and financial accountability for US Oncology clinical operations budgets.

Skills

Leadership experience

Oncology strategy

Data-driven delivery

Cross-functional collaboration

Portfolio management

Real-world evidence

People management

AI in trials

Education

Bachelor’s degree in life sciences / related field

Advanced degree (Master’s/PhD/PharmD/MD)

Job description

GSK is seeking a Sr Director, Global Monitoring & Site Engagement (GMASE), US Oncology Head to accelerate US Oncology trial delivery and broaden patient access, including non-traditional and community-based settings. This leader will drive continuous evidence generation and partner across Clinical, Medical, Regulatory, and DS&M to ensure high-quality, timely trial outcomes.

The role demands extensive oncology trial leadership, deep therapeutic insight, and a track record of executing complex,