Senior Director, Theranostics & Radiation Science

AstraZeneca; United States; On-site; USD 260,000 - 420,000; Full time

Job summary

AstraZeneca is seeking a Senior Director, Theranostics and Radiation Science in the United States. The role leads as a senior medical physicist, directing Radiation Science team development and cross-functional collaboration across imaging and radioconjugate development, regulatory affairs, and clinical operations.

Responsibilities include dosimetry framework leadership, vendor management, health authority interactions, and pipeline oversight from biodistribution studies to late-phase

Qualifications

• Bachelor’s degree in physics, mathematics, engineering, or another physical science, followed by a Ph.D. in medical physics, physics, or a related scientific discipline (required).
• Completion of a medical physics residency or equivalent postdoctoral training, followed by 10+ years of post-training clinical and/or industry experience in nuclear medicine, molecular imaging, or radiopharmaceutical development, including 3-5 years in industry (required).
• Board certification in medical physics (e.g., ABR, CCPM, or equivalent) preferred but not required.
• Extensive experience with personalized dosimetry for radiopharmaceuticals and proficiency in imaging/dosimetry tools (required).
• Deep understanding of radiation biology/physics, including alpha- and beta-emitting radioconjugates (required).

Responsibilities

• Lead imaging and dosimetry strategy across the Radiation Science portfolio, from early to late-phase development.
• Provide line management, mentorship, and career development for Radiation Science team members.
• Own external imaging and dosimetry vendor relationships, including selection, scope, and budgets.
• Represent Radiation Science in health authority interactions and regulatory submissions content.
• Oversee imaging protocol development, QC parameters, dose determination, and reconstruction processes.
• Ensure imaging execution support at clinical sites and adherence to study protocols.
• Lead regulatory compliance efforts related to radioactive materials and stay current with guidelines.
• Represent the organization in scientific societies, publications, and collaborations.

Skills

Leadership

Dosimetry

Imaging expertise

Regulatory collaboration

Programming (MATLAB/Python)

Nuclear medicine imaging

Education

PhD in medical physics or related

Medical physics residency

Bachelor’s in physics/engineering

Tools

OLINDA

MIM

Python

MATLAB

DICOM/PACS

Job description

AstraZeneca is seeking a Senior Director, Theranostics and Radiation Science in the United States. The role leads as a senior medical physicist, directing Radiation Science team development and cross-functional collaboration across imaging and radioconjugate development, regulatory affairs, and clinical operations.

Responsibilities include dosimetry framework leadership, vendor management, health authority interactions, and pipeline oversight from biodistribution studies to late-phase