Senior Director, Theranostics & Radiation Imaging

AstraZeneca plc; Wilmington (DE); On-site; USD 234,000 - 350,000; Full time

Benefits offered by this job

Bonus opportunity

Equity-based incentives

401(k) plan

Health benefits

Job summary

AstraZeneca, a leader in Early Oncology Research and Development, seeks a Senior Director of Theranostics and Radiation Science to guide medical physics strategy and team development. You will own dosimetry frameworks and manage cross-functional engagement across imaging, regulatory affairs, and clinical operations.

The role requires deep expertise in medical physics, dosimetry, and regulatory submissions, with a track record in leadership and vendor management.

Qualifications

• Board certification in medical physics preferred but not required.
• Extensive experience with personalized dosimetry for radiopharmaceuticals.
• Proficiency with imaging and dosimetry tools (OLINDA, MIM).

Responsibilities

• Lead imaging and dosimetry strategy across the Radiation Science portfolio.
• Provide line management, mentorship, and career development for Radiation Science team members.
• Own external imaging and dosimetry vendor relationships, including vendor selection, scope and budget, performance management, and escalation.
• Serve as Radiation Science lead in health authority interactions on dosimetry and imaging, and own the dosimetry and imaging content of regulatory submissions.
• Oversee optimization and review of nuclear medicine imaging protocols, including QC, dose determination, and protocol dose management.
• Oversee imaging execution support at clinical sites, ensuring adherence to study protocols.
• Oversee QC protocols and their execution with internal/external partners for imaging review and processing.
• Perform, review, and oversee image-based, patient-specific dosimetry calculations (internal dosimetry).
• Represent Radiation Science with senior leadership and cross-functional partners; ensure regulatory compliance.

Skills

Medical physics leadership

Dosimetry

Team mentorship

Vendor management

Regulatory interactions

Analytical skills

MATLAB

Python

DICOM

PACS

Education

Ph.D. in medical physics or related field

Medical physics residency/postdoc training

Bachelors in physics/physical science

Tools

OLINDA

MIM

DICOM

PACS

Job description

AstraZeneca, a leader in Early Oncology Research and Development, seeks a Senior Director of Theranostics and Radiation Science to guide medical physics strategy and team development. You will own dosimetry frameworks and manage cross-functional engagement across imaging, regulatory affairs, and clinical operations.

The role requires deep expertise in medical physics, dosimetry, and regulatory submissions, with a track record in leadership and vendor management.