Senior Director, Technical Services - T1D Cell Therapy

Vertex Pharmaceuticals; Boston (MA); Hybrid; USD 217,000 - 325,000; Full time

Job summary

Vertex Pharmaceuticals is seeking a Senior Director, Head of Technical Services for T1D Cell Therapy External Manufacturing Operations in Boston and Portsmouth. The role leads real-time GMP manufacturing support, troubleshooting, investigations, and readiness for process changes to enable compliant, efficient cell therapy production.

The ideal candidate will have extensive cell therapy manufacturing experience, strong people leadership, and a track record of partnering across Manufacturing,

Qualifications

• 15+ years of relevant industry experience in biotechnology, biopharmaceutical, cell therapy, or related manufacturing environments.
• 8+ years of progressive people leadership experience.
• Experience leading manufacturing-facing technical support in a GMP-regulated environment.
• Strong experience with deviations, investigations, troubleshooting, batch support, change implementation.
• Proven ability to influence across Manufacturing, Quality, Engineering, Supply Chain, and process science organizations.

Responsibilities

• Lead the Technical Services function supporting GMP manufacturing of cell-derived therapies for Type 1 Diabetes.
• Provide technical leadership for cell therapy manufacturing operations.
• Serve as the senior technical escalation point for manufacturing issues affecting batch execution, product quality, cycle time, or supply reliability.
• Lead technical troubleshooting and support timely resolution of deviations, investigations, atypical events, and process excursions.
• Drive operational process monitoring and trend review to identify emerging risks, improve execution consistency, and enhance manufacturing performance.
• Own Technical Services readiness for process changes, campaign startup, new product introduction, and transferred processes entering GMP manufacturing.
• Partner closely with Manufacturing, Quality Assurance, Quality Control, Engineering, Supply Chain, Regulatory, and CMC teams to support robust execution and inspection readiness.
• Build, develop, and mentor a high-performing team of technical subject matter experts supporting manufacturing operations.
• Foster a culture of quality, accountability, technical rigor, collaboration, inclusion, and patient focus.

Skills

Cell therapy manufacturing

People leadership

Cross-functional collaboration

Technical troubleshooting

Process change implementation

Education

Advanced degree in Bioengineering or related field

Job description

Vertex Pharmaceuticals is seeking a Senior Director, Head of Technical Services for T1D Cell Therapy External Manufacturing Operations in Boston and Portsmouth. The role leads real-time GMP manufacturing support, troubleshooting, investigations, and readiness for process changes to enable compliant, efficient cell therapy production.

The ideal candidate will have extensive cell therapy manufacturing experience, strong people leadership, and a track record of partnering across Manufacturing,