Senior Director, Technical Services - T1D Cell Therapy Ops

Biopharma Careers; Boston (MA); Hybrid; USD 217,000 - 325,000; Full time

Job summary

Vertex is seeking a Senior Director, Head of Technical Services for T1D Cell Therapy External Manufacturing Operations to lead the manufacturing-facing technical function across clinical and commercial operations. The Head provides leadership for real-time manufacturing support, investigations, process monitoring, and readiness for changes in GMP manufacturing.

This role requires deep cell therapy manufacturing expertise, strong cross-functional influence, and a track record of building

Qualifications

• 15+ years of relevant industry experience in biotechnology, biopharmaceutical, cell therapy, or other advanced therapy manufacturing environments.
• 8+ years of progressive people leadership experience, including experience leading managers and cross-functional technical teams.
• Demonstrated success leading manufacturing-facing technical support in a GMP-regulated environment.
• Strong experience with deviations, investigations, troubleshooting, batch support, change implementation, and operational problem-solving.
• Proven ability to influence across Manufacturing, Quality, Engineering, Supply Chain, and process science organizations.

Responsibilities

• Lead the Technical Services function supporting GMP manufacturing of cell-derived therapies for Type 1 Diabetes.
• Provide technical leadership for cell therapy manufacturing operations
• Serve as the senior technical escalation point for manufacturing issues affecting batch execution, product quality, cycle time, or supply reliability.
• Lead technical troubleshooting and support timely resolution of deviations, investigations, atypical events, and process excursions.
• Drive operational process monitoring and trend review to identify emerging risks, improve execution consistency, and enhance manufacturing performance.
• Own Technical Services readiness for process changes, campaign startup, new product introduction, and transferred processes entering GMP manufacturing.
• Partner with Manufacturing, Quality Assurance, Quality Control, Engineering, Supply Chain, Regulatory, and CMC teams to support robust execution and inspection readiness.
• Build, develop, and mentor a high-performing team of technical subject matter experts supporting manufacturing operations.
• Foster a culture of quality, accountability, technical rigor, collaboration, inclusion, and patient focus.

Skills

Leadership experience

GMP knowledge

Cross-functional collaboration

Problem solving

Education

Advanced degree in related field

Job description

Vertex is seeking a Senior Director, Head of Technical Services for T1D Cell Therapy External Manufacturing Operations to lead the manufacturing-facing technical function across clinical and commercial operations. The Head provides leadership for real-time manufacturing support, investigations, process monitoring, and readiness for changes in GMP manufacturing.

This role requires deep cell therapy manufacturing expertise, strong cross-functional influence, and a track record of building