Senior Director Global Oral Solid Dosage Forms (Global OSD), Technical Operations, Science & Innovation

AstraZeneca; City of Mount Vernon (NY); Hybrid; USD 210,000 - 314,000; Full time

Benefits offered by this job

Executive leadership

Global exposure

Job summary

AstraZeneca seeks a Senior Director Global OSD to lead global technical operations for the Oral Solid Dosage portfolio. Based in Newark/Mt. Vernon, you will drive strategy, develop leaders, and promote Lean, data-driven improvements across sites and partners.

You will manage budgets, coach senior staff, and shape innovations in material science and pharmaceutics to sustain manufacturing excellence and product availability.

Qualifications

• Broad drug development and commercialization knowledge across lifecycle stages.
• OSD-specific experience in development, manufacturing and scale-up.
• OSD manufacturing technology expertise with strong process insight.
• Solid understanding of SHE, cGMP and Lean principles.
• Experience leading in Operations and/or R&D within a matrix, with lean leadership.
• Strong communication and stakeholder relationship building.

Responsibilities

• Lead and develop a global technical organisation for OSD commercial portfolio.
• Coach reports, build capability, and promote continuous improvement.
• Shape regional strategy and translate it into actionable plans.
• Ensure robust product/process performance and risk management.
• Leverage data, AI and analytics to drive improvements and innovation.
• Oversee budgeting, headcount and revenue for the team.

Skills

Drug development

OSD expertise

OSD manufacturing

Scientific breadth

SHE

cGMP

Lean

Operations leadership

R&D experience

Matrix organization

Lean leadership

Communication skills

Stakeholder management

Global leadership

CDC expertise

AI analytics

Digital solutions

Tech transfer

Material science

Pharmaceutics

Technology introduction

Team leadership

Talent development

Budget management

Capital planning

Job description

Job Title: Senior Director Global Oral Solid Dosage Forms (Global OSD), Technical Operations, Science & Innovation

Location: Mt. Vernon, US - However, we could also consider Newark as a potential location for this role.

Hybrid working model: 3 days per week in the office location

Introduction to role:

Are you ready to lead a team that makes a difference in the pharmaceutical industry? This senior leadership role provides strategic and operational direction for the global organisation responsible for on-market technical support to AstraZeneca's commercial Oral Solid Dosage (OSD) portfolio.

Based in Newark, US, with frequent office presence in Mt. Vernon. The position leads a high-performing team that supports OSD platform teams and senior scientific experts, ensuring robust, reliable and innovative manufacturing performance across the product lifecycle.

How will you shape the future of OSD manufacturing, harnessing science, digital tools and Lean ways of working to deliver medicines that truly matter?

Accountabilities

In this role, the Senior Director Global OSD leads and develops a diverse technical organisation focused on delivering strong product and process performance for AstraZeneca's commercial OSD portfolio.

The position manages and coaches direct reports, building capability, engagement and succession while fostering a culture of continuous improvement and innovation.

As a key member of the North Americas Commercial Operations Leadership Team, the role shapes regional strategy, aligns cross-functional priorities and translates strategy into clear, actionable plans that drive value across the network.

The Senior Director is accountable for proactively managing product and process robustness, using data, AI and advanced analytics to generate insights and drive performance improvements. The role develops and implements science and innovation strategies for OSD manufacturing, with particular emphasis on material science, pharmaceutics and new technology introduction in partnership with Manufacturing Technology and Product Development.

A critical part of the remit is to maintain a best-in-class technical support model for internal manufacturing sites and external partners, ensuring outstanding customer service and effective risk management. The Senior Director sets clear direction, communicates with impact and influences at all levels to embed Lean principles, operational excellence and compliant ways of working across the function.

The role also carries financial accountability for the team's budget, including headcount and revenue, ensuring resources are deployed effectively to deliver strategic priorities. Operating confidently in a global environment, the Senior Director builds an organisation ready for future challenges and change, contributing significantly to the success of Operations and the commercial viability and availability of current products.

Essential Skills/Experience

• Have an excellent understanding of the overall drug development and commercialization process from development, launch and through life cycle management
• Extensive pharmaceutical proven experience specifically in relation to Oral Solid Dosage (OSD) form drug products.
• Have a broad understanding of the various scientific subject areas that they have accountability for with expert knowledge of Oral Solid Dosage form manufacturing technology.
• Have a detailed understanding of principles, applications and management of SHE, cGMP and Lean.
• Experience in Operations and/or R&D with a track record of successful project leadership and delivery within a matrix organization and lean leadership.
• Evidence of excellent communication skills and build excellent relationships with customers/key partners.

Essential Skills/Experience

• Proven experience leading large, multi-site or global technical organisations within commercial manufacturing
• Extensive experience in the application and industrialisation of innovative manufacturing technologies, with preference for expertise in continuous manufacturing platforms, particularly Continuous Direct Compression (CDC)
• Demonstrated success in deploying AI, digital or sophisticated analytics solutions to improve manufacturing performance
• Successful leadership of new technology introduction across pharmaceutical development and commercial manufacturing networks
• Strong background in material science or pharmaceutics applied to OSD development or commercialisation
• Experience introducing new technologies or platform capabilities into commercial operations at scale
• Track record of building high-performing, inclusive teams and developing senior technical leaders
• Demonstrable experience overseeing substantial budgets and leading investment decisions within a complex operational environment. An understanding of capital planning and the budgeting lifecycle-encompassing forecasting, prioritisation, approval governance, and performance tracking-would be highly advantageous.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

AstraZeneca offers the chance to work at the intersection of pioneering science, digital innovation and Lean operations, where complex challenges are tackled with rigor, curiosity and collaboration. Here, ideas move quickly from concept to reality; investment in technology, skills and development opens up varied global career paths; and work on medicines that address unmet needs brings a strong sense of purpose. Colleagues support one another across generations and backgrounds, sharing knowledge, challenging assumptions and constantly learning as they help transform molecules into medicines for patients worldwide.

The annual base pay for this position ranges from $209,559.20 - $314,338.80 Annual USD. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program. Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an "at-will position" and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.