Senior Director, GCS Early Pipeline & BD — Hybrid

Vertex US Distribution; Boston (MA); Hybrid; USD 240,000 - 360,000; Full time

Job summary

Vertex Pharmaceuticals is seeking a Senior Director/Director to lead the global commercial assessment for two priority pre-clinical Sandbox diseases. You will build deep market understanding, size opportunities by geography and patient segment, and forecast revenue for future assets.

The role requires strategic thinking, cross-functional leadership, and the ability to translate data into actionable development guidance.

Qualifications

• Experience developing commercial opportunity assessments for pre-clinical or early-development assets.
• Ability to build detailed market models including patient-based forecasts and pricing assumptions.
• Proven ability to communicate complex data to executives and guide strategic decisions.
• Experience collaborating across Research, External Innovation, Development, Medical, Regulatory, Value & Access, Finance, and analytics teams.

Responsibilities

• Serve as global commercial lead for two pre-clinical Sandbox diseases, owning the commercial assessment and disease strategy.
• Develop market sizing, forecasting, and commercial requirements by geography and patient segment.
• Lead primary market research with healthcare professionals, patients, payers, and other stakeholders.
• Translate scientific and market data into clear executive recommendations for development decisions.
• Collaborate with cross-functional teams to shape disease priorities and translational plans.

Skills

Commercial strategy

Market forecasting

Stakeholder engagement

Market research

Team leadership

Education

MD or PhD in science/medicine

MBA valued

Job description

Vertex Pharmaceuticals is seeking a Senior Director/Director to lead the global commercial assessment for two priority pre-clinical Sandbox diseases. You will build deep market understanding, size opportunities by geography and patient segment, and forecast revenue for future assets.

The role requires strategic thinking, cross-functional leadership, and the ability to translate data into actionable development guidance.