Senior Director, Drug Substance Eng. & Materials Science

Scorpion Therapeutics; Boston (MA); On-site; USD 150,000 - 210,000; Full time

Job summary

Vertex is seeking a talented leader to join the Engineering and Materials Science department in Boston, MA. The successful candidate will lead a diverse team of engineers and scientists and contribute to the development and scale-up of drug substance and drug product candidates.

This role emphasizes cross-functional collaboration, process development, scale-up, technology transfer to manufacturing partners, and advancing regulatory dossiers.

Qualifications

• Advanced degree in materials science/chemistry with pharma materials development experience.
• Five years of team management experience.

Responsibilities

• Lead cross-functional team to define and demonstrate multi-step syntheses for manufacturing APIs from clinical to launch.
• Lead drug substance process development, modeling, and tech transfer to contract manufacturers.
• Collaborate across materials science, chemistry, analytics, and formulation to optimize drug substance properties.
• Promote adoption of process modeling.
• Lead projects across pharmaceutical sciences.
• Mentor junior scientists and promote best practices.
• Influence strategic direction of the department.
• Communicate across interdisciplinary teams.

Skills

Team leadership

Pharmaceutical process development

Unit operations

Process modeling

QbD concepts

Regulatory dossiers

Communication skills

Education

BS in Materials Science/Chemistry

MS in Materials Science/Chemistry

PhD in Materials Science/Chemistry

5 years management experience

Job description

Vertex is seeking a talented leader to join the Engineering and Materials Science department in Boston, MA. The successful candidate will lead a diverse team of engineers and scientists and contribute to the development and scale-up of drug substance and drug product candidates.

This role emphasizes cross-functional collaboration, process development, scale-up, technology transfer to manufacturing partners, and advancing regulatory dossiers.