Senior Director, Clinical Science

Barrington James; United States; On-site; USD 100,000 - 130,000; Full time

Job summary

Barrington James is seeking a Senior Director Clinical Science for a six-month contract, with potential for permanence. The position demands significant experience in clinical development, particularly in cardiology, overseeing clinical trials and leading data reviews while collaborating with cross-functional teams.

Qualifications

• Advanced degree in a clinical or scientific discipline required.
• Minimum 7 years’ experience in clinical development.
• Board-certified cardiologist or relevant experience.

Responsibilities

• Primary contact for medical inquiries from sites and monitors.
• Support clinical science lead and collaborate with operations.
• Conduct literature reviews and standardize clinical documents.

Skills

Interpersonal skills

Communication skills

Clinical judgment

Team collaboration

Education

PharmD, PhD, or MD

Job description

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Barrington James is partnered with a small cardiology focussed biotech looking for a Senior Director Clinical Science on a 6 month contract with the possibility to the go permanent.

Key responsibilities include:

• Serve as primary contact for medical inquiries from sites, CROs, and monitors; triage or respond as needed.
• Act as clinical science lead, supporting the Medical Director and interfacing internally and externally.
• Collaborate with Clinical Operations on site selection and start-up activities.
• Support or review clinical presentation materials for internal/external meetings (e.g., IMs, SIVs, Advisory Boards).
• Assist in data collection and preparation of abstracts, posters, and publications.
• Contribute to clinical document development (protocols, CSRs, IBs, briefing books); conduct literature reviews and standardize disease/molecule language.
• Perform clinical data reviews using tools like SAS, Spotfire, and Rave; collaborate with Data Management on queries.
• Attend Safety Review Meetings; support safety data tracking and analysis across studies.
• Draft clinical narratives for submissions and final study reports.
• Help develop Investigator Meeting agendas and support CRO/site monitor training.

Ideal candidate would:

• Advanced degree in a clinical or scientific discipline required (e.g., PharmD, PhD, MD).
• Minimum of 7 years’ experience in clinical development within the pharmaceutical industry.
• Board-certified cardiologist or significant relevant experience in cardiology.
• Proven experience in clinical database review and data cleaning.
• Strong background in briefing book preparation and Phase 3 study design.
• Hands-on experience in managing Phase 2 and Phase 3 clinical trials.
• Demonstrated clinical judgment with the ability to clearly articulate complex medical concepts.
• Skilled in working collaboratively within cross-functional teams.
• Strong interpersonal and communication skills, with the ability to engage effectively across organizational levels and with external stakeholders (e.g., investigators, CROs, vendors).

Seniority level

• Seniority level

  Director

Employment type

• Employment type

  Contract

Job function

• Job function

  Research and Science

• Industries

  Pharmaceutical Manufacturing and Biotechnology Research

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