Senior Director, Clinical Operations — Global Trial Leader

Hemab Therapeutics; Cambridge (MA); Hybrid; USD 250,000 - 320,000; Full time

Job summary

Hemab Therapeutics is seeking a Senior Director of Clinical Operations to drive end-to-end delivery of a growing sutacimig portfolio from first-in-human studies to pivotal trials. The role reports to the VP Clinical Operations and the CEO with a Boston-based hybrid work setup requiring 2–3 days in the office.

The candidate will lead a high-performing clinical operations team, own budgeting, and develop scalable processes, ensuring trials meet timelines and quality standards while advancing

Qualifications

• Bachelor's degree in life sciences or related field.
• Strong command of ICH/GCP and international regulatory requirements.
• 15+ years of clinical operations/clinical program management experience in pharmaceutical or biotech.
• 10+ years in a management or functional leadership role.
• Proven track record of on-time, on-budget trial delivery in complex global programs.
• Excellent cross-functional collaboration and executive communication skills.
• Deep expertise in early and late-phase trial design and execution.
• Experience managing and optimizing CRO and vendor relationships.
• Registration (BLA/MAA) submission experience.
• Recognized as an influential and respected leader within the organization and industry.

Responsibilities

• Drive end-to-end operational delivery across a growing global portfolio, from first-in-human studies to pivotal trials.
• Own end-to-end operational execution of clinical trials from protocol finalization through clinical study report; ensure delivery on time, within budget, and to high quality standards.
• Lead budget ownership across the program including forecasting, tracking, and actively managing spend.
• Build and evolve processes and SOPs that scale with the organization and reflect industry best practice.
• Establish data-driven reporting mechanisms for trial status, risks, and performance metrics.
• Lead cross-functional collaboration and executive communication across Hemab.
• Join and represent the asset at board of directors meetings for updates and reviews.
• Identify and implement process innovations including decentralized or hybrid trial components.

Education

Bachelor's degree or higher in life sciences, biology, or related field

Job description

Hemab Therapeutics is seeking a Senior Director of Clinical Operations to drive end-to-end delivery of a growing sutacimig portfolio from first-in-human studies to pivotal trials. The role reports to the VP Clinical Operations and the CEO with a Boston-based hybrid work setup requiring 2–3 days in the office.

The candidate will lead a high-performing clinical operations team, own budgeting, and develop scalable processes, ensuring trials meet timelines and quality standards while advancing