Senior Director, CDMO & Manufacturing Strategy

Vertex Pharmaceuticals; Boston (MA); Hybrid; USD 218,000 - 328,000; Full time

Benefits offered by this job

Hybrid work flexibility

Executive-level exposure

Job summary

Vertex Pharmaceuticals is seeking a Senior Director, Business Operations Lead to steer product-level manufacturing leadership within CMTO. You will partner across Strategic Sourcing, Manufacturing Operations, Legal, and Finance to align contracts with product priorities and drive governance on performance.

This role demands extensive experience in regulated manufacturing, cost oversight, and strategic planning, with a focus on readiness, network decisions, and supply continuity.

Qualifications

• Significant experience in biotechnology, pharmaceutical, or other highly regulated industry.
• Experience supporting manufacturing, external manufacturing, CDMO management, or technical operations.
• Experience with product-level business management in a manufacturing environment, including governance, cost oversight, performance monitoring, and cross-functional decision support.
• Proven experience with COGM assessment, tracking, and cost improvement planning.
• Experience leading or contributing to governance forums tied to manufacturing performance, supply strategy, and business risk.
• Demonstrated ability to operate in a matrixed environment and influence cross-functional stakeholders.

Responsibilities

• Serve as the Business Operations lead for assigned product(s) within CMTO and provide product-level business leadership.
• Act as business lead in the CDMO relationship, representing priorities and requirements.
• Lead product-level governance on manufacturing performance against KPIs.
• Define requirements for readiness and growth and monitor progress to plan.
• Maintain end-to-end business understanding of CDMO/site performance and implications for strategy.
• Establish and evolve product-level KPIs focusing on cost, efficiency, service, and performance.
• Develop dashboards and reporting for governance and leadership reviews.
• Own responsibility for COGM and track progress against reduction plans.
• Drive product-level decisions on capacity, sourcing, continuity, and risk.

Skills

CDMO management

Governance forums

COGM

Cost oversight

KPIs

Scenario planning

Contracting

Cross-functional leadership

Financial acumen

Excel/Power BI

Education

Bachelor’s degree in Business, Finance, Engineering, Life Sciences

Tools

SAP

Power BI

Tableau

Smartsheet

Job description

Vertex Pharmaceuticals is seeking a Senior Director, Business Operations Lead to steer product-level manufacturing leadership within CMTO. You will partner across Strategic Sourcing, Manufacturing Operations, Legal, and Finance to align contracts with product priorities and drive governance on performance.

This role demands extensive experience in regulated manufacturing, cost oversight, and strategic planning, with a focus on readiness, network decisions, and supply continuity.