Senior Director, Bioanalysis Leadership & CRO Strategy

Madrigal Pharmaceuticals Inc.; Conshohocken (Montgomery County); On-site; USD 241,000 - 295,000; Full time

Benefits offered by this job

Equity

Comprehensive benefits

401(k) employer match

Employee Assistance Program (EAP)

Job summary

Madrigal Pharmaceuticals Inc. is seeking a Senior Director of Bioanalytical Sciences to define and lead bioanalytical strategies across multiple programs.

You will partner with CROs to ensure high-quality data, oversee assay development and validation, and support regulatory submissions with robust scientific rationale. The role requires extensive experience in LC-MS/MS and immunoassay methods, with a track record of global regulatory compliance and cross-functional leadership in a fast-paced

Qualifications

• Ph.D. or advanced degree in analytical chemistry, pharmaceutical sciences or related field preferred.
• 15+ years of experience in bioanalytical sciences for clinical and nonclinical programs.
• Proven success leading bioanalytical activities in outsourced/CRO-based models.
• Strong scientific judgment with ability to influence cross-functional stakeholders.

Responsibilities

• Define and implement bioanalytical strategies across programs with external partnerships to support clinical and nonclinical development.
• Select, manage, and evaluate CRO partners for quality, timelines and budget.
• Develop scalable CRO partnering strategy including assay transfer and lifecycle management.
• Oversee assay development, qualification, validation, and sample analysis by external partners.
• Lead regulatory submissions and regulator engagement for IND/CTA and NDA/BLA.

Skills

LC-MS/MS

Bioanalytical method development

Immunoassays

Ligand binding

Regulatory knowledge

Education

PhD or equivalent

Job description

Madrigal Pharmaceuticals Inc. is seeking a Senior Director of Bioanalytical Sciences to define and lead bioanalytical strategies across multiple programs.

You will partner with CROs to ensure high-quality data, oversee assay development and validation, and support regulatory submissions with robust scientific rationale. The role requires extensive experience in LC-MS/MS and immunoassay methods, with a track record of global regulatory compliance and cross-functional leadership in a fast-paced