Senior Data Scientist, Genomics - Cambridge

Novartis Group Companies; Cambridge (MA); On-site; USD 126,000 - 234,000; Full time

Job summary

Novartis Group Companies in Cambridge, MA seeks a highly motivated computational scientist to apply human genetics and genomic data science to drug discovery. You will work with geneticists and disease-area scientists to generate actionable insights for target discovery and patient selection across CVM diseases.

You will analyze sequencing data, develop methods for variant prioritization, and contribute to patient stratification efforts while integrating multi-omics data to guide translational

Qualifications

• PhD with 2-3+ years or MS with 6+ years in human genetics, statistical genetics, computational biology, bioinformatics, epidemiology, biostatistics, or related field.
• Postdoctoral experience preferred.

Responsibilities

• Analyze whole exome/genome sequencing data to identify variants, genes, and pathways related to CVM diseases.
• Develop statistical genetics and bioinformatics methods for variant annotation, association, burden testing, and gene prioritization.
• Support identification, evaluation, and validation of novel therapeutic targets using genetic evidence and genomic data.
• Contribute to patient selection and stratification strategies for research programs with genetically defined subgroups.
• Integrate genetics results with transcriptomic, proteomic, and clinical data to derive insights.
• Collaborate with cross-functional teams to define analytical strategies and translate findings into recommendations.
• Develop reproducible, well-documented analytic workflows and contribute to best practices in genomic data analysis.
• Communicate results through presentations, reports, manuscripts, and project updates.
• Stay current with advances in genetics and computational methods for drug discovery.

Skills

Human genetics

Statistical genetics

Computational biology

Bioinformatics

Python

R

Linux

PostgreSQL/SQL

Genotype-phenotype

Education

PhD with 2-3+ years or MS with 6+ years

Tools

Git

Job description

Novartis Group Companies in Cambridge, MA seeks a highly motivated computational scientist to apply human genetics and genomic data science to drug discovery. You will work with geneticists and disease-area scientists to generate actionable insights for target discovery and patient selection across CVM diseases.

You will analyze sequencing data, develop methods for variant prioritization, and contribute to patient stratification efforts while integrating multi-omics data to guide translational