Senior Data Engineer - Build Trusted Cancer Data Pipelines

BioSpace

Durham (NC)

On-site

USD 118,000 - 157,000

Full time

8 days ago

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Benefits offered by this job

401(k) plan
Medical, dental, vision
Flexible time-off

Job summary

GRAIL is seeking a Senior Data Engineer for its Operational Technology team in RTP, North Carolina. You’ll own data pipelines linking lab instruments, automation systems, and platforms to a trusted data foundation.

This senior role requires hands-on development, architecture definition, and collaboration across engineering, lab operations, and data science teams. You will mentor engineers, improve data quality, and enforce standards while supporting analytics, dashboards, and governed AI

Qualifications

  • Degree in Computer Science, Mathematics, Software Engineering, Data Science, Life Sciences, Physics or similar field.
  • BS/BA degree with 5+ years or Master's degree with 3+ years of relevant experience in data engineering, analytics engineering, or software development.
  • Advanced proficiency in SQL, including performance optimization and complex transformation logic.
  • Strong proficiency with one or more programming languages, such as Python, Rust, C++, or similar.
  • Solid understanding of ETL/ELT pipeline design, relational databases, data modeling, and structured or semi-structured data.
  • Demonstrated ability to own data pipelines and infrastructure end to end and to work independently on problems of diverse scope.
  • Strong attention to detail and a commitment to data quality, reliability and accuracy.
  • Ability to collaborate effectively with, and advise, both technical and non-technical individuals, and comfort working in a rapidly changing environment with dynamic objectives and fast iteration.
  • Ability to investigate complex technical problems methodically, continuously learn, and communicate clearly to a range of audiences.
  • A highly analytical mindset and eagerness to solve difficult technical problems.

Responsibilities

  • Architect, build, and maintain complex data pipelines that ingest and integrate information from laboratory instruments, automation systems, sequencers, operational platforms, APIs, autonomous robotics platforms, databases and file based data sources.
  • Own critical pipelines and data models end to end, from design through production operation, working independently on problems of diverse scope and adapting existing approaches where limited precedent exists.
  • Define and evolve the data architecture, modeling standards, and engineering patterns that the broader team builds on, and drive adoption across the group.
  • Support downstream analytics, reporting, and AI systems by delivering clean, trustworthy datasets and timely data extracts for troubleshooting, root-cause investigations and platform improvements.
  • Develop and optimize advanced SQL and transformation logic to cleanse, standardize, and model raw instrument and production data into reliable, well structured datasets.
  • Build and support datasets and data models used by operational dashboards, analytics, process monitoring, troubleshooting, and governed AI enabled workflows.
  • Design and implement orchestration, testing, monitoring and alerting so that data failures, freshness issues, schema changes, and incomplete processing are identified and resolved early.
  • Establish and enforce data validation and quality standards to ensure datasets are accurate, complete, and reliable across the platform.
  • Partner with and advise systems engineers, lab operations, data scientists, and automation engineers on difficult technical matters, adapting your communication for both technical and non-technical stakeholders.
  • Mentor and provide technical guidance to junior engineers, and contribute to the team's overall engineering practices and standards.
  • Document pipelines, data models, and datasets to support reproducibility and compliance with ISO, CLIA, CAP, NYS, GMP, and FDA requirements.
  • Continuously improve your technical skills and the team's engineering practices.

Skills

SQL
Python
Rust
C++
ETL/ELT
Data modeling
Anlytical mindset
Communication

Education

BS/BA in CS/Math/SE/Data Science/Physics or similar
MS in CS/related field (optional)

Tools

Airflow
dbt
AWS S3
Redshift
Glue
Snowflake

Job description

GRAIL is seeking a Senior Data Engineer for its Operational Technology team in RTP, North Carolina. You’ll own data pipelines linking lab instruments, automation systems, and platforms to a trusted data foundation.

This senior role requires hands-on development, architecture definition, and collaboration across engineering, lab operations, and data science teams. You will mentor engineers, improve data quality, and enforce standards while supporting analytics, dashboards, and governed AI

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