Senior Clinical Trial Manager — Hybrid/Remote Global Trials

Disc Medicine; Massachusetts; Hybrid; USD 151,000 - 185,000; Full time

Job summary

Disc Medicine is seeking a Sr. Clinical Trial Manager to lead start-up and execution of large, global trials in a fast-growing biotech setting. The role supports in-office and remote team members, oversees CROs and vendors, and drives study timelines and budgets in a fully outsourced model.

Strong GCP knowledge and cross-functional collaboration are required. Reporting to the Associate Director of Clinical Operations, you will partner with investigators worldwide, travel as needed, and

Qualifications

• BA/BS required and 7+ years of clinical trial experience.
• Experience with phase III oncology studies.
• Proficient in FDA/EMA/ICH GCP guidelines and regulatory processes.
• Willingness to travel domestically and internationally.
• Strong cross-functional collaboration and vendor management.

Responsibilities

• Manage start-up and execution of global clinical trials.
• Oversee CROs and vendors, including budgets and timelines.
• Prepare and review clinical documents (protocols, ICFs, brochures, DSURs).
• Ensure audit-ready trial master file and GCP compliance.
• Coordinate investigator meetings and sponsor-site communications.
• Monitor progress and travel to sites/CROs as needed.

Education

BA/BS degree

Tools

Microsoft Office

Electronic data systems

Job description

Disc Medicine is seeking a Sr. Clinical Trial Manager to lead start-up and execution of large, global trials in a fast-growing biotech setting. The role supports in-office and remote team members, oversees CROs and vendors, and drives study timelines and budgets in a fully outsourced model.

Strong GCP knowledge and cross-functional collaboration are required. Reporting to the Associate Director of Clinical Operations, you will partner with investigators worldwide, travel as needed, and