Senior Clinical Scientist, Neuro Sleep (Phase 1/2)

Centessa Pharmaceuticals, a wholly owned subsidiary of Eli Lilly and Company

Boston (MA)

On-site

USD 140,000 - 225,000

Full time

3 days ago

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Benefits offered by this job

401(k) plan

Medical insurance

Dental insurance

Vision insurance

Paid time off

Wellness program

Job summary

Centessa Pharmaceuticals is seeking an (Associate) Director, Clinical Science to lead design, execution, and interpretation of early-stage (Phase 1/2) trials for Orexin-targeted programs in neurodegeneration and neuropsychiatric conditions. You will partner with Clinical Development, Regulatory Affairs, Biostatistics, and Safety teams, shaping strategy and high-quality study execution.

Reporting to the Executive Director, Clinical Development, you will author key clinical/regulatory documents,

Qualifications

Advanced scientific/clinical degree required (PhD or PharmD).
8-10 years of clinical research/development experience in biotech/pharma.
Experience leading early-phase (Phase 1/2) trials and cross-functional teams.

Responsibilities

Serve as clinical scientist lead on early-stage trials (Phase 1/2) for Orexin-targeted programs.
Contribute to clinical development plan design, dose-escalation, and data interpretation.
Lead development and review of key clinical and regulatory documents (protocols, IBs, CSRs, briefing materials).
Serve as study medical/scientific lead from start-up to study report completion.
Drive safety/PK/PD and biomarker data interpretation to inform decisions.
Provide scientific leadership in governance forums and cross-functional discussions.