Senior Clinical Pharmacologist - PK/PD Leader

AbbVie Inc.; San Francisco (CA); On-site; USD 180,000 - 250,000; Full time

Job summary

AbbVie Inc. Clinical Pharmacology and Pharmacometrics (CPPM) seeks a lead PK scientist to conceive and execute novel PK/PD research, generate proposals, and advance methods in PK/PD.

You will act as a senior expert, evaluate regulatory advances, and integrate knowledge into research and development programs. The role supports Phase 1–4 studies, writes regulatory documents, conducts data analyses, and presents at conferences.

Qualifications

• PhD with 0 years of experience, or Pharm D with 2+ years of experience in a relevant field, Master’s Degree or equivalent education and typically 8+ years of experience, Bachelor’s Degree or equivalent education and typically 10+ years of experience; (*relevant field includes experience with PK, PBPK, PK-PD, Pharmacometrics or systems pharmacology, Drug metabolism/Transporters)

Responsibilities

• Contribute to clinical development by supporting Phase 1-4 studies including study design, and clinical pharmacology strategy.
• Author regulatory documents including protocols, study reports, population PK reports, exposure-response analyses reports, relevant section of investigator brochures, common technical documents, white papers, and other similar documents.
• Conduct data analyses including non-compartmental analyses, modeling and simulation, literature data analyses.
• Participate and present at various departmental and cross functional teams such as study teams, clinical pharmacology and biopharmaceutics, clinical strategy team, Clinical Pharmacology leadership team, Journal club.
• Collaborate with scientific support from other Clinical Pharmacology functional groups to provide a unified clinical pharmacology position to clinical, CMC and regulatory teams.
• Author scientific publications and present at scientific conferences.

Skills

PK/PD modeling

PBPK

Pharmacometrics

Systems pharmacology

Education

PhD in a relevant field

PharmD with 2+ years

Master’s Degree or equivalent

Bachelor’s Degree or equivalent

Job description

AbbVie Inc. Clinical Pharmacology and Pharmacometrics (CPPM) seeks a lead PK scientist to conceive and execute novel PK/PD research, generate proposals, and advance methods in PK/PD.

You will act as a senior expert, evaluate regulatory advances, and integrate knowledge into research and development programs. The role supports Phase 1–4 studies, writes regulatory documents, conducts data analyses, and presents at conferences.