Senior Clinical Data Management Trial Lead

Merck; West Point (PA); On-site; USD 142,000 - 224,000; Full time

Benefits offered by this job

Annual bonus

Long-term incentive

Medical, dental, vision coverage

401(k) retirement plan

Job summary

Merck is seeking a Clinical Data Management Trial Lead to drive end-to-end data management for assigned studies, ensuring quality, integrity, and regulatory compliance. You will provide strategic and operational oversight across the trial lifecycle and serve as the primary data management contact for cross-functional teams.

The role requires deep CDM expertise, leadership, and strong knowledge of CDISC standards, with responsibility for UAT, data standards, and inspection readiness in a global

Qualifications

• 10+ years of direct data management experience in clinical trials.
• Proven leadership of end-to-end CDM activities across lifecycle.
• Strong knowledge of CDISC standards and regulatory expectations.

Responsibilities

• Lead end-to-end CDM activities from start-up to archival per SOPs and ICH‑GCP.
• Oversee data collection design, validation, and remediation across sources.
• Ensure integrity across data sources (EDC, eCOA, external data) and traceability.
• Own risk-based data quality oversight; mitigate risks and protect timelines.
• Manage data acquisition/integration and validation specs aligned with protocol.
• Represent data management in cross-functional governance and CTT forums.

Skills

CDM

Influencing

Interpersonal

Project Leadership

Risk Management

Strategic Thinking

Team Organization

English Communication

Education

Non-Degree/Associate (preferred in Nursing/Pharmacy/Life sciences)

Bachelor's Degree (preferred in Nursing/Pharmacy/Life sciences)

Advanced Degree (Masters/Doctorate) (preferred)

Tools

EDC systems

eCOA

Data Reconciliation

Data Integration

Data Visualization

Query Management

Job description

Merck is seeking a Clinical Data Management Trial Lead to drive end-to-end data management for assigned studies, ensuring quality, integrity, and regulatory compliance. You will provide strategic and operational oversight across the trial lifecycle and serve as the primary data management contact for cross-functional teams.

The role requires deep CDM expertise, leadership, and strong knowledge of CDISC standards, with responsibility for UAT, data standards, and inspection readiness in a global