Senior Bioinformatics Software Engineer

BigRio; Town of Texas (WI); Remote; USD 40,000 - 80,000; Full time

Job summary

Join a forward-thinking company as a Senior Bioinformatics Software Engineer, where you'll play a crucial role in developing innovative software solutions for bioinformatics pipelines. Collaborate with diverse teams to create data-driven applications that enhance scientific research. This position offers the opportunity to work remotely while contributing to cutting-edge projects in a dynamic environment. If you are passionate about bioinformatics and software development, this role is perfect for you, allowing you to make a significant impact in the field.

Qualifications

• 5+ years in software development with bioinformatics focus.
• Experience designing scalable software solutions.
• Proficient in multiple programming languages.

Responsibilities

• Develop and maintain software solutions for bioinformatics pipelines.
• Collaborate with cross-functional teams for data-driven solutions.
• Optimize database performance and ETL processes.

Skills

Python

Perl

R

Bash

SQL

NoSQL

Agile Development

Git

CI/CD

API Development

Education

Bachelor's degree in Computer Science

Master's degree in Bioinformatics

Tools

Azure

Docker

Kubernetes

Nextflow

Git

Job description

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Sr. Director, Talent Acquisition and HR at BigR.io

Senior Bioinformatics Software Engineer

Location: Remote (CST Hours) –TX

Duration: Full-Time

About BigRio:

BigRio is a remote-based, technology consulting firm with headquarters in Boston, MA. We deliver software solutions ranging from custom development and software implementation to data analytics and machine learning/AI integrations. As a one-stop shop, we attract clients from a variety of industries due to our proven ability to deliver cutting-edge, cost-effective software solutions.

Position Summary:

The Senior Bioinformatics (BI) Software Engineer plays a critical technical role in the design, development, and maintenance of scalable and efficient software solutions for bioinformatics pipelines. This position requires close collaboration with cross-functional teams to deliver data-driven software solutions that align with business objectives.

Key Responsibilities:

• BI Development: Build and maintain reliable software solutions using diverse technologies and databases to meet business requirements.
• Data Modeling: Develop and refine data models to ensure computational algorithm performance and integrity, particularly in areas like genome assembly, mapping, variant calling, and annotation.
• ETL Processes: Design and enhance ETL processes to extract, transform, and load data efficiently, often through API-based integrations.
• Query Optimization: Optimize SQL queries and database performance. Participate in schema design and review processes to maintain high performance and scalability.
• Dashboard & Report Creation: Create interactive dashboards and automated reports using tools like Azure Pipelines, Power Automate, and Nextflow to support data-driven decision-making.
• Collaboration: Work closely with stakeholders, such as analysts, clinicians, lab staff, and developers, to understand needs and deliver timely software solutions.
• Data Integration: Integrate diverse data sources, ensuring accuracy and reliability while minimizing code debt and maintaining system flexibility.
• Quality Assurance: Perform rigorous testing and automate test suites (e.g., with pytest, doctest, Azure Pipelines) to ensure software quality and stability.
• Documentation & Maintenance: Produce clear, comprehensive documentation including inline code comments, wikis, READMEs, and trace mappings to ensure ease of use and maintainability.

Qualifications:

• Education: Bachelor’s degree in Computer Science, Software Engineering, Bioinformatics, or related field (Master’s preferred).
• Experience: Minimum of 5 years in software development, with experience designing and implementing scalable, production-ready software solutions. Experience working with lab scientists, computational biologists, or clinical professionals is a plus.

Technical Skills:

• Proficient in at least two programming languages (Python, Perl, R, or Bash preferred; Java, C++, Groovy also acceptable).
• Strong background in database systems such as SQL Server, NoSQL, MongoDB, MySQL, or ElasticSearch.
• Agile development experience with Git and CI/CD implementation. Knowledge of Azure is a plus.
• Comfortable with object-oriented programming and software architecture design best practices.
• Skilled in writing well-tested, maintainable, production-ready code with a strong focus on unit and integration testing.
• Exceptional at writing documentation and translating scientific concepts into accessible code annotations or supporting documentation.
• Experience designing and building APIs and microservices from scratch.
• Familiarity with Linux and HPC environments (e.g., SLURM, Kubernetes, GCP, Azure) is beneficial.
• Knowledge of package managers (PIP, Conda) and containerization tools (Docker, Singularity).
• Exposure to workflow management/orchestration tools (e.g., Nextflow, Airflow, Snakemake) is a plus.
• Excellent analytical thinking with the ability to translate complex problems into clear technical solutions and communicate them effectively.
• Strong team player with excellent communication skills, open to feedback, and focused on collaborative problem-solving.
• Flexible and adaptable, with a proactive approach to learning new technologies and implementing best practices in software development.
• Capable of independently managing project timelines and communicating effectively through changing project scopes.

Equal Opportunity Statement:

BigRio is an equal-opportunity employer. We prohibit discrimination and harassment of any kind based on race, religion, national origin, sex, sexual orientation, gender identity, age, pregnancy, status as a qualified individual with disability, protected veteran status, or other protected characteristic as outlined by federal, state, or local laws. BigRio makes hiring decisions based solely on qualifications, merit, and business needs at the time. All qualified applicants will receive equal consideration for employment.

Seniority level

• Seniority level

  Mid-Senior level

Employment type

• Employment type

  Full-time

Job function

• Industries

  Software Development

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