Senior Bioinformatics Scientist — Multi-Omics & AI Immunology

AstraZeneca; Cambridge (MA); On-site; USD 116,000 - 173,000; Full time

Job summary

AstraZeneca seeks a bioinformatics scientist to translate complex omics data into actionable insights supporting antigen design and translational strategies. You will work with immunologists, molecular biologists, and data scientists in a Cambridge, MA environment, designing reproducible pipelines on HPC and cloud platforms.

The role emphasizes integrating LLM-powered agentic workflows, guiding study designs, and delivering publication-quality visuals while maintaining robust version control and

Qualifications

• PhD with 2–5 years of industry experience or MS with 4–6 years in bioinformatics/genomics.
• Proficiency in R and/or Python for genomic data analysis and data visualization.
• Hands-on experience with NGS data analysis and variant calling workflows.

Responsibilities

• Design, implement, and deliver analyses across genomics, transcriptomics, and multi-omics.
• Apply ML and statistical modeling to biomarkers and patient stratification; build scalable workflows on HPC/AWS.

Skills

PhD in Bioinformatics

Python for genomic analysis

R for genomic data analysis

Machine learning basics

Education

PhD in Bioinformatics, Computational Biology, Genomics, Molecular Biology, CS

Tools

STAR

BWA

Bowtie2

GATK

SAS/SQL

Job description

AstraZeneca seeks a bioinformatics scientist to translate complex omics data into actionable insights supporting antigen design and translational strategies. You will work with immunologists, molecular biologists, and data scientists in a Cambridge, MA environment, designing reproducible pipelines on HPC and cloud platforms.

The role emphasizes integrating LLM-powered agentic workflows, guiding study designs, and delivering publication-quality visuals while maintaining robust version control and