Senior Bioinformatics & Genomics Data System Engineer

Natera; United States; Remote; USD 114,000 - 142,000; Full time

Benefits offered by this job

Remote work

Competitive benefits

Job summary

Natera is seeking a Senior Bioinformatics & Genomics Data System Engineer to join the DSPE DevOps team. You will design, develop, test, deploy, maintain, and update DSPE software tools, data platforms, and automation systems in a mostly remote setup.

The role requires strong Python, bioinformatics knowledge, and AWS experience, with emphasis on scalable production systems and cross-functional collaboration. Excellent communication and documentation skills are essential.

Qualifications

• Bachelor's degree in Computer Science, Software Engineering, Bioinformatics, or related field; advanced degrees preferred.
• 3+ years in regulated environment (e.g., CLIA/FDA) for Bachelor's; 3+ years with Master's; 2+ years with Doctorate.
• 3+ years in Software Engineering or DevOps teams.
• Experience creating design specs, verification/validation docs, and user manuals.

Responsibilities

• Design, develop, test, deploy, maintain, and update DSPE software tools and data/cloud/automation systems.
• Maintain and optimize software/system performance across key metrics like CPU, RAM, I/O, and disk usage.
• Create architecture and infrastructure design documents for scalable deployments.
• Contribute to technical documentation and training materials for DSPE tools and systems.
• Train and coach DSPE team members on new technologies and best practices.
• Represent DSPE Software Engineering & DevOps in stakeholder meetings.

Skills

Bioinformatics concepts

NGS technologies

Python programming

AWS cloud services

Linux command line

Git workflow

Automation development

Performance optimization

SDLC & testing

Production software development

Education

Bachelor's degree in CS/SE/Bioinformatics

Tools

AWS Batch

AWS ECS

S3

EC2

GitHub

GitLab

PostgreSQL

MySQL

BCL/FASTQ/BAM/VCF

Job description

US Remote

As a Senior Bioinformatics & Genomics Data System Engineer of our Data Science Production Engineering (DSPE) department, you will be a key member in the DSPE DevOps team, to design, develop, test, deploy, maintain, and update DSPE's software tools, data platforms, cloud platforms, automation systems, and analytics systems.

PRIMARY RESPONSIBILITIES:

Technical

• Ensure the timely and efficient delivery of software tools and systems with correct and robust functionality.
• Contribute to key design, development, testing, deployment, validation, maintenance, and update activities for DSPE's software tools and data/cloud/automation systems.
• Working with DSPE leadership teams, create suitable system architecture and infrastructure design documents that can be efficiently implemented and maintained.
• Maintain and optimize software/system performance, by monitoring and studying different solutions' impacts on key system metrics, such as network I/O, disk I/O, RAM usage, CPU usage, disk space usage, etc.

Quality, Compliance, and Documentation

• Contribute to technical documentation's creation, maintenance, and updates for the DSPE Software Engineering & DevOps-team owned software tools and systems.
• Create training materials, and contribute to training activities, for the DSPE Software Engineering & DevOps team-owned software tools and systems.

Cross-Functional

• Train and coach DSPE team members on new technologies, procedures, and guidelines/best practices.
• Represent the DSPE Software Engineering & DevOps team in stakeholder meetings.

QUALIFICATIONS:

• Minimal Bachelor's Degree in Computer Science, Software Engineering, Bioinformatics, or a related field. Advanced degrees preferred.
• Minimal 6 years of relevant industry experience for candidates with only a Bachelor's Degree. Minimal 3 years of relevant industry experience for candidates with a Master's Degree. Minimal 2 years of relevant industry experience for candidates with a Doctorate degree.
• Minimal 3 years of working experience in a highly regulated environment, e.g., CLIA and/or FDA compliant settings.
• Minimal 3 years of working experience in a Software Engineering, or a DevOps team.
• Demonstrable experience in developing and maintaining custom-developed software tools or systems for production environments, preferable in high-throughput settings (e.g., heavy traffic and/or high computational load).
• Demonstrable experience in creating software design specification documents, verification and validation documents, and user manuals.

KNOWLEDGE, SKILLS, AND ABILITIES:

• Excellent understanding of key bioinformatics and genomics concepts, and NGS technologies.
• Excellent Python programming skills, with demonstrable bioinformatics or genomics application and/or automation system development experience.
• Excellent understanding of AWS services relevant to bioinformatics and genomics applications.
• Working experience with key AWS services, such as Batch, ECS, S3, EC2, HealthOmics, etc., preferably in developing for-production software tools/systems.
• Proficient with RDBMS systems such as PostgreSQL and/or MySQL, and demonstrable working experience in for-production database-based application development.
• Working experience with bioinformatics and genomics-specific file types, such as BCL, FASTQ, BAM, VCF files.
• Working knowledge in optimizing system architecture and individual components for performance, scalability, and/or reliability, especially for genomics-scale data.
• Working knowledge in tool/system performance evaluation methods, and familiar with the key factors, such as RAM, Disk IO, Network IO's impact on system/tool's performance, especially for bioinformatics and genomics applications.
• Working knowledge in SDLC and software development and testing methodologies.
• Working knowledge in Linux command line skills, and past Linux application development experience.
• Proficiency in Git workflow and version control systems like GitHub and/or GitLab.
• Past experience in developing automation solutions.

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.

Remote USA

$113,600 - $142,000 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

If you are based in California, we encourage you to read this important information for California residents.

Please be advised that Natera will reach out to candidates with a @ natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes serious, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey.Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiringprocess or thereafter. Any information that you do provide will be recorded and maintained in aconfidential file.

As set forth in Natera’s Equal Employment Opportunity policy,we do not discriminate on the basis of any protected group status under any applicable law.

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection.As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measurethe effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categoriesis as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.