Senior Bioconjugates Scientist – Downstream Processing

jj

United States

On-site

USD 140,000 - 210,000

Full time

7 days ago
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Job summary

Johnson & Johnson in Malvern, PA is seeking a Senior Scientist, Bioconjugates, Downstream Processing to lead development activities for antibodies and bioconjugates such as tLNP, ADC, AOC, and APC within the API-Large Molecule group. You will design experiments, optimize chromatography, filtration, and conjugation steps, and transfer technologies to partners.

You will collaborate across teams, document data, and ensure project milestones are met, with occasional weekend work required.

Qualifications

  • PhD with 3+ years post-doctoral experience or MS with 12+ years or BS with 15+ years required.
  • Experience in downstream processing and purification of antibodies/recombinant protein therapeutics including conjugation.
  • Analytical method development for in-process methods preferred.

Responsibilities

  • Lead experimental design and optimize steps for target process scale (lab to pilot).
  • Design and execute development studies for chromatography, filtration, and conjugation.
  • Record, analyze, and report data; prepare technical documents and transfer tech to partners.
  • Collaborate in a team while meeting project timelines and objectives.

Skills

Downstream processing
Antibody purification
Conjugation chemistry
Analytical method development
Data reporting
Written records
Team collaboration
Project management

Education

PhD in Chemical Engineering or Biological Sciences
MS in Chemical Engineering or Biological Sciences
BS in Chemical Engineering or Biological Sciences

Tools

Chromatography systems
Filtration equipment

Job description

Johnson & Johnson in Malvern, PA is seeking a Senior Scientist, Bioconjugates, Downstream Processing to lead development activities for antibodies and bioconjugates such as tLNP, ADC, AOC, and APC within the API-Large Molecule group. You will design experiments, optimize chromatography, filtration, and conjugation steps, and transfer technologies to partners.

You will collaborate across teams, document data, and ensure project milestones are met, with occasional weekend work required.

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