Senior Automation Engineer - Syncade MES (GMP)

Biogen, Inc.; Northern (KY); Hybrid; USD 93,000 - 121,000; Full time

Benefits offered by this job

Medical insurance

Dental insurance

Vision insurance

Life insurance

401(k) with company match

Tuition reimbursement

Job summary

Biogen is seeking a Senior Automation Engineer I to join the Automation Systems Engineering team at the RTP site. The role focuses on Syncade MES administration within a GMP-regulated manufacturing environment, with responsibilities covering configuration, troubleshooting, lifecycle management, and cross-system integration.

The successful candidate will lead MES-related investigations, manage access and audit trails, and drive improvements in system reliability and usability, while supporting

Qualifications

• Bachelor’s degree in Engineering required.
• 5–8+ years of automation engineering in a regulated environment (GMP preferred).
• Minimum 3 years of Syncade/MES infrastructure, workflows, eBR design, and manufacturing process support.
• Strong understanding of GxP compliance, data integrity, and change control processes.
• Proven ability to independently troubleshoot and resolve complex technical issues.

Responsibilities

• Act as system administrator/SME for Syncade (MES), including configuration, maintenance, troubleshooting, and lifecycle management.
• Own and support Syncade application and infrastructure to enable eBR workflows, recipe configuration, and exception handling.
• Ensure system availability, performance, and data integrity to support GMP manufacturing operations.
• Lead root cause investigations and implement corrective/preventive actions for MES-related deviations.
• Manage user access, security roles, and audit trail reviews in compliance with GxP and cybersecurity requirements.
• Execute and support change controls, including system updates, enhancements, and validation deliverables (IQ/OQ/PQ).
• Drive continuous improvement to enhance system usability, reliability, and operational efficiency.
• Support integration and data flow between Syncade and other automation/enterprise systems (DeltaV, PI, Infobatch, CMMS, Oracle, Veeva, LIMS).
• Provide technical support during manufacturing operations, including off-hours support as required.

Skills

Automation engineering

Regulated environment

Syncade/MES

GxP compliance

Change control

Root-cause analysis

System administration

Education

Bachelor’s degree in Engineering

Tools

DeltaV

PI System

Infobatch

Job description

Biogen is seeking a Senior Automation Engineer I to join the Automation Systems Engineering team at the RTP site. The role focuses on Syncade MES administration within a GMP-regulated manufacturing environment, with responsibilities covering configuration, troubleshooting, lifecycle management, and cross-system integration.

The successful candidate will lead MES-related investigations, manage access and audit trails, and drive improvements in system reliability and usability, while supporting