Senior Associates Scientist - Genotyping

BioSpace; Village of Tarrytown (NY); On-site; USD 80,000 - 131,000; Full time

Job summary

Regeneron is seeking a Scientist to join the Genotyping Group in Tarrytown, NY. You will genotype complex GM models using state-of-the-art platforms to support R&D and drug discovery.

Responsibilities include high-throughput DNA isolation, qPCR setup on Hamilton and Beckman liquid handlers, data analysis with LIMS, and reporting results to collaborators. Experience with rodent genetics and automation is preferred.

Qualifications

• Minimum of 3 years of biology/molecular biology experience.
• Bachelor's or Master's degree in biology, molecular biology, or related sciences.
• Strong scientific rigor and curiosity in rodent genetics.
• Preferred experience in screening or automation laboratories and familiarity with coding (R, Python, Shiny).

Responsibilities

• Process biopsy samples for DNA extraction and genotyping analysis.
• Use high-throughput automation to isolate DNA from stem cells and rodent samples.
• Select and implement genotyping methods to prioritize workflows.
• Operate Hamilton and Beckman liquid handlers for qPCR setup and master mix preparation.
• Coordinate multiple steps to begin aliquoting qPCR master mixes.
• Set up complex qPCR reactions across multiple platforms.
• Run qPCR and analyze data with custom tools; report results via LIMS.
• Perform conventional PCR or Southern Blotting as needed.
• Maintain sample management systems and assay inventory.

Skills

Rodent genetics

Automation know-how

Coding (R, Python, Shiny)

Ambiguity handling

Education

Bachelor's or Master's in biology or related

Tools

Hamilton Liquid Handler

Beckman i7 Liquid Handler

LIMS

Job description

Build Our Future Together

We are looking for a motivated Scientist to join the Genotyping Group at VelociGene. As a Scientist, your primary responsibility will be genotyping complex genetically modified models utilizing state-of-the-art technology platforms to support our R&D and Technology Development efforts for drug discovery.

This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

When & Where

Location: Tarrytown, NY United States

Discover Your Role

• Processing biopsy samples for downstream extraction and genotyping analysis.
• Using high-throughput automation for DNA isolation from embryonic stem cells and rodent biopsies.
• Strategically selecting and implementing genotyping methodologies to establish workflow priorities.
• Operating applications that create worklists for qPCR assay retrieval and bulk master mix preparation on Hamilton Liquid Handler.
• Orchestrating multiple processes to begin the aliquoting of qPCR master mixes.
• Setting up complex qPCR reactions across multiple Beckman i7 Liquid Handlers.
• Initiating qPCR using the state-of-the-art customized cycling platform.
• Collecting, organizing, and analyzing raw data files with custom data analysis tools.
• Reporting genotyping results through LIMS and initiating discussions with collaborators if needed.
• Performing conventional PCR or Southern Blotting Techniques as a genotyping alternative to qPCR.
• Maintaining comprehensive sample management systems and assay inventory effectively.

This Role Requires

• Can multi-task assignments and operate effectively in the face of ambiguity and change.
• Bachelors or Masters degree in biology, molecular biology, or related biological sciences with a minimum of 3 years of experience.
• Are highly motivated with a genuine curiosity for rodent genetics.
• Maintain scientific rigor and familiarity with best practices.
• Leverage automation to drive scientific advancement.
• Drive innovation by developing novel approaches and optimizing existing platforms to increase efficiency and data quality.
• Preferred: Prior experience in a screening laboratory and/or automation laboratory.
• Preferred: Knowledge of coding languages (R, Python, Shiny web framework).

We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually)

$80,300.00 - $131,100.00