Senior Associate Scientist Process Chemistry

Pfizer; United States; On-site; USD 69,000 - 114,000; Full time

Benefits offered by this job

Relocation support

Pfizer benefits

Job summary

Pfizer seeks a synthetic organic chemist to join the Process Chemistry group in Groton, CT. You will design and execute routes for drug candidates, including peptides and lipids, ensuring scalable, safe, and robust processes.

Strong communication and thorough literature familiarity are required to document results and contribute to cross-functional teams. The role involves collaboration with manufacturing and tech transfer, with opportunities to impact API synthesis from discovery to early

Qualifications

• Master's degree in Chemistry with laboratory-based research experience required.
• Demonstrated high performance in synthetic organic chemistry experimentation.
• Excellent oral and written communication skills, including the ability to maintain an accurate scientific notebook.
• Familiarization with modern analytical tools and techniques, as well as data interpretation.
• Thorough working knowledge of the published literature in synthetic organic chemistry.
• An ability to communicate results through clear, concise written reports, publications and related documentation.
• Prior peptide and lipid synthesis experience is highly valued, particularly route development, scale-up, purification strategies and cross-functional collaboration.

Responsibilities

• Assist in design and execution of synthetic routes to drug candidates including small molecules, peptides and lipids.
• Develop safe, efficient, robust and scalable processes in a team-oriented environment.
• Support experimental studies from small-scale discovery to commercial routes and tech transfer readiness.
• Communicate results through written reports and participate in cross-functional teams.

Skills

Synthetic organic chemistry

Analytical methods

Experimental design

Scientific writing

Data interpretation

Peptide synthesis

Lipid synthesis

Cross-functional collaboration

Safety compliance

Education

Master's degree in Chemistry

Tools

NMR

LC-MS

HPLC

Job description

ROLE SUMMARY

We are seeking a synthetic organic chemist to join the Process Chemistry group within Chemical Research and Development (CRD) in Groton, CT. CRD, part of Preclinical and Translational Sciences within Pfizer R&D, is responsible for the development of process technology to produce active pharmaceutical ingredients (APIs). This work includes the synthesis of diverse chemical entities that support both traditional small molecules and emerging therapeutic modalities, including peptides, lipids and other complex synthetic molecules. CRD scientists engage in all facets of development from small scale synthesis in support of discovery programs, to the development of the commercial synthetic routes. CRD scientists partner with manufacturing specialists for API synthesis in kilo-lab and pilot plant facilities, as well as provide support for technology transfer to Pfizer manufacturing sites and third-party facilities.

ROLE RESPONSIBILITIES

The successful candidate will work in the laboratory and assist in the design and execution of synthetic routes to drug candidates including traditional small-molecules, peptides, lipids, and other complex synthetic modalities, within a dynamic, team-oriented environment and assist in the development and completion of experimental studies to provide safe, efficient, robust and scalable processes.

A strong working knowledge of synthetic organic chemistry principles, excellent laboratory skills, an awareness of analytical methods, and a commitment to safety are required. Compliance on safety and regulatory requirements is expected and documented through our internal training program.

The candidate should thrive in the collaborative environment of a multi-disciplinary project team. A willingness to learn and apply new technology to process development challenges is required.

QUALIFICATIONS

• Master's degree in Chemistry with laboratory-based research experience required. Pharmaceutical industry experience is preferred but not required.
• Demonstrated high performance in synthetic organic chemistry experimentation with a strong working knowledge of synthetic organic chemistry principles.
• Excellent oral and written communication skills, including the ability to maintain an accurate scientific notebook.
• Familiarization with modern analytical tools and techniques, as well as data interpretation.
• Thorough working knowledge of the published literature in synthetic organic chemistry.
• An ability to communicate results through clear, concise written reports, publications and related documentation.
• Prior experience with peptide and lipid synthesis is highly valued, particularly hands-on experience with route development, scale-up, purification strategies, and cross-functional collaboration in support of pharmaceutical research and development, though it is not required.

PHYSICAL/MENTAL REQUIREMENTS

• Laboratory work requires standing.
• Working at a computer.

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

• Travel is required on occasion in support of external manufacture or to participate in scientific conferences.
• Relocation support available
• Work Location Assignment: On Premise
• The annual base salary for this position ranges from $68,600.00 to $114,300.00.
• In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 7.5% of the base salary.
• We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments.
• Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage.
• Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com).
• Pfizer compensation structures and benefit packages are aligned based on the location of hire.
• The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
• Relocation assistance may be available based on business needs and/or eligibility.
• Candidates must be authorized to be employed in the U.S. by any employer.
• U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with informati