Senior Associate Scientist, Neuroscience Translational Discovery

Bristol-Myers Squibb; Georgia; On-site; USD 70,000 - 110,000; Full time

Job summary

An established industry player is seeking a Senior Associate Scientist for their Neuroscience Translational Discovery team. This role involves developing biomarker assays and supporting drug candidates' progression towards clinical trials. You will work in a collaborative environment, engaging in meaningful research that aims to transform the lives of patients with neurodegenerative diseases. The position offers a chance to contribute to groundbreaking therapeutic developments while working alongside talented professionals. If you're passionate about science and eager to make a difference, this is an exciting opportunity to advance your career.

Benefits

Competitive benefits

Flexible work environment

Opportunities for career growth

Qualifications

• 4+ years of experience with a Bachelor's or 2+ years with a Master's.
• Hands-on experience in immunoassays and molecular assays.

Responsibilities

• Develop target engagement and biomarker assays for early development.
• Prepare data packages for phase 1 studies and support neuro projects.

Skills

Immunoassay techniques

Molecular assays

Data analysis and interpretation

Biomarker development

Communication skills

Education

Bachelor’s Degree

Master’s Degree

Tools

ELISA

qPCR

RNAseq

Job description

Senior Associate Scientist, Neuroscience Translational Discovery

Senior Associate Scientist, Neuroscience Translational Discovery

Apply locations Cambridge Crossing - MA - US time type Full time posted on Posted 13 Days Ago job requisition id R1590940

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

The Neuroscience TRC is committed to the development of transformational therapeutics for patients with neurodegenerative, neuropsychiatric and neuromuscular diseases. A network of external partnerships paired with internal discovery of small molecules, biologics and genetic medicines supports our ambition to become leaders in neuroscience. Internal research focuses on causal human biology linking the immune system, protein clearance and synaptic mechanisms with nervous system disorders, applying human cells, AI, ML and high-throughput biology to identify and validate novel mechanisms.

Areas of interest include, but are not limited to, the identification of disease modifying and symptomatic therapies for neurodegenerative, neuropsychiatric, neuroinflammatory and neuromuscular diseases; approaches to modulate protein clearance and reduce or eliminate toxic protein production; emerging technologies (RNA, DNA targeting) that when matched to underlying causal human biology may deliver a precision medicine portfolio with a high probability of translational success. We emphasize identification of neuroimaging and fluid biomarkers to track disease progression, target engagement and therapeutic response in our discovery and clinical programs.

Position Summary:

The Neuroscience Thematic Research Center (Neuro TRC) leverages external collaborations and internal research to establish a diverse portfolio targeting unmet needs in neurodegenerative, neuropsychiatric, neuroinflammatory and neuromuscular diseases. The Senior Associate Scientist, Translational Discovery, in collaboration with other members of the Neuro TRC, undertakes design and delivery of translational data packages that enable rapid progression of drug candidates towards clinical proof-of-concept. This position is based in Cambridge, MA, and is primarily a laboratory-based role.

Position Responsibilities:

• Work closely with the team to develop target engagement and biomarker assays for assets in early development.
• Drive biomarker assay qualification with CROs.
• In collaboration with Global Biospecimen Inventory Management, manage TRC specimens for target engagement and biomarker development.
• Prepare data packages to support target engagement and biomarker data inclusion for phase 1 studies.
• Work closely, in collaboration with in-house science teams, on study designs, data analyses, interpretation that support high priority neuro projects/programs.
• Draft and review internal project reports as needed; present scientific data at internal and external conferences.

Basic Qualifications:

• Bachelor’s Degree
  
  • 4+ years of academic and / or industry experience

Or

• Master’s Degree
  
  • 2+ years of academic and / or industry experience

Preferred Qualifications:

• Hands on experience in immunoassay and molecular assays (ELISA, Meso-scale discovery, SIMOA, qPCR, dd-PCR, RNAseq, etc.).
• Experience in managing biorepositories.
• Proven track record in designing, troubleshooting, analyzing and interpreting data from translational and experimental medicine type studies.
• Experience transferring assay to contract research organizations for analysis in multi-site clinical trials.
• Deep understanding of unmet need and clinical outcome measures used in studies focused on neurodegenerative disorders.
• Excellent oral and written communication skills.
• Ability to work both independently and as a well-integrated member of multidisciplinary drug development teams.

#LI-Onsite

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.