Senior Associate Scientist – Injectable Drug Product Development

AstraZeneca plc; Cambridge (MA); Presencial; USD 65 000 - 95 000; Tempo integral

Resumo da oferta

AstraZeneca plc in Cambridge, MA seeks an Associate Scientist II to join the Injectable Drug Product Development (IDPD) team within PDCS. You will perform experimental work on drug product formulation and process development to support manufacturing and characterization, including analytical and biophysical comparability testing.

The role requires designing, executing studies, maintaining records, preparing development reports, and collaborating with cross-functional teams to drive timely

Qualificações

• BS or MS degree in Biochemistry, Pharmaceutical Science, Chemical Engineering, or relevant field with 2 to 4 years relevant work experience
• Scientific and practical knowledge of protein/peptide biochemistry, protein formulation, and stability
• Experience with imaged capillary electrophoresis (iCE/Maurice), H/UPLC’s (IEX, SEC), DLS, CD, DSC, AUC, and NanoTemper
• Ability to execute experiments with minimal supervision and work in a collaborative setting with timelines
• Excellent interpersonal, collaborative and communication skills; initiative in problem solving

Responsabilidades

• With some supervision, design and execute formulation and process development studies for clinical biologic candidates
• Execute drug development studies including physico-chemical characterization and stability studies for clinical and commercial drug products
• Characterize conformational and colloidal stability using industry standard methods (e.g., CD, DLS, DSC, AUC)
• Maintain organized records and use team tools to keep multiple assignments on track
• Assist in the preparation of internal technical reports on executed studies with minimal supervision
• Participate in cross-functional development teams

Conhecimentos

Protein biochemistry

Formulation & stability

Collaborative teamwork

Analytical testing familiarity

MS Office proficiency

Formação académica

BS or MS in Biochemistry/Pharmaceutical Science/ChE

Ferramentas

iCE/Maurice

H/UPLC (IEX, SEC)

DLS

CD

DSC

AUC

NanoTemper

Descrição da oferta de emprego

AstraZeneca plc in Cambridge, MA seeks an Associate Scientist II to join the Injectable Drug Product Development (IDPD) team within PDCS. You will perform experimental work on drug product formulation and process development to support manufacturing and characterization, including analytical and biophysical comparability testing.

The role requires designing, executing studies, maintaining records, preparing development reports, and collaborating with cross-functional teams to drive timely