Senior Associate Scientist – Drug Discovery & Synthesis

Iambic; San Diego (CA); In loco; USD 84.000 - 120.000; Tempo pieno

Descrizione del lavoro

We are seeking a highly skilled and motivated Senior Associate Scientist to join the Chemistry team at Iambic Therapeutics headquarters in San Diego.

This laboratory-based role requires strong expertise in organic synthesis, catalysis, and medicinal chemistry, collaborating with medicinal chemists, biologists, DMPK scientists, computational chemists, ML researchers, and software engineers across discovery stages.

Competenze

• BS in Chemistry with 5+ years experience (pharma/biotech) or MS in Chemistry with 3+ years experience (pharma/biotech).
• Proven skills in multi-step organic synthesis, reaction optimization, SAR analysis, and scientific presentation.
• Ability to thrive in a fast-paced, highly collaborative research environment.
• Availability to work onsite in San Diego.

Mansioni

• Design, synthesize, purify, and characterize chemical compounds (10 mg–5 g scale) using modern analytical techniques such as LCMS, HPLC, and NMR, employing both individual and automated parallel synthesis approaches.
• Identify and optimize reaction conditions using screening kits and other streamlined methodologies.
• Collaborate with the high-throughput experimentation team to ensure the successful execution of parallel chemistry experiments.
• Analyze biological and ADME-PK data using cheminformatics tools and contribute to data-driven discussions and strategic planning.
• Partner with computational chemists to leverage machine learning insights for efficient execution of the design-make-test cycle and platform development.
• Present results to project teams and senior leadership, clearly communicating data, implications, and recommendations.

Conoscenze

Organic synthesis

Reaction optimization

SAR analysis

Scientific presentation

Team collaboration

Formazione

BS in Chemistry + 5+ years pharma/biotech

MS in Chemistry + 3+ years pharma/biotech

Descrizione del lavoro

We are seeking a highly skilled and motivated Senior Associate Scientist to join the Chemistry team at Iambic Therapeutics headquarters in San Diego.

This laboratory-based role requires strong expertise in organic synthesis, catalysis, and medicinal chemistry, collaborating with medicinal chemists, biologists, DMPK scientists, computational chemists, ML researchers, and software engineers across discovery stages.