Senior Associate Scientist - Conjugation Process Development

Pfizer; Bothell (WA); On-site; USD 69,000 - 114,000; Full time

Benefits offered by this job

401(k) plan with matching

Health benefits

Paid vacation/leave

Relocation assistance (eligible)

Job summary

Pfizer in Bothell, WA seeks a Senior Associate Scientist (R2) for Conjugation Process Development within Bioprocess R&D. The role involves developing robust ADC conjugation processes, transferring technology to clinical and commercial sites, and supporting manufacturing campaigns with strong documentation and collaboration.

Required BS/BA in chemical-related fields with 3–4 years experience or MS with 0–2 years.

Qualifications

• Must have a BS/BA in Chemistry, Biochemistry, Chemical/Biochemical Engineering or related fields with 3–4 years of experience, or an MS with 0–2 years.
• Practical knowledge of bioconjugation, protein purification, analytical biochemistry, and scale up is preferred.
• Experience with GLP/GMP practices and technology transfers to manufacturing sites is advantageous.

Responsibilities

• Design, plan, and execute milligram to gram-scale conjugation experiments in the development laboratory.
• Ensure timely, effective, and high-quality documentation in ELNs and technical reports.
• Communicate results to stakeholders and present data to colleagues and management.
• Assist in or lead technology transfer of manufacturing processes to clinical and commercial facilities.
• Provide support and troubleshoot during manufacturing campaigns.
• Collaborate cross-functionally to maintain safe, efficient lab operations.

Skills

Conjugation techniques

Bioconjugation

Protein purification

Analytical biochemistry

Scale up

GLP/GMP practices

Technology transfer

Education

BS/BA in Chemistry/Biochemistry/Chemical Engineering

MS in related fields

Job description

What You Will Achieve

A Senior Associate Scientist (R2) position is available in the Conjugation Process Development group of Bioprocess R&D in USA- WA- Bothell. We’re seeking a passionate and creative individual to join a dynamic team of scientists and engineers focused on developing robust, scalable, and high productivity conjugation processes for the manufacture of antibody‑drug conjugates (ADCs) for early‑and‑late‑phase clinical programs. The work will also involve working with commercial and clinical production facilities to ensure accurate technology transfer and successful large‑scale production. You may also be involved in cutting‑edge technology development projects that seek to discover new innovations for ADC process development and/or manufacturing.

How You Will Achieve It

• Design, plan, and execute milligram to gram‑scale conjugation experiments in the development laboratory.
• Ensures timely, effective, and high‑quality documentation in electronic laboratory notebooks and internal technical reports.
• Communicate results and findings to stakeholders on a regular basis; present data/strategy to colleagues and management in internal and external venues (technical meetings, project team meetings, and conferences, etc.) as appropriate.
• Assist in or lead the technology transfer of manufacturing processes to clinical and commercial manufacturing facilities.
• Provide support and troubleshoot during manufacturing campaigns as needed.
• Work collaboratively with colleagues both within the group and cross‑functionally; contribute to maintaining and improving upon our safe, effective and efficient lab operations.

Qualifications

Must-Have BS/BA in Chemistry, Biochemistry, Chemical/Biochemical Engineering, or other related disciplines with 3-4 years of experience, or MS in the above fields with 0-2 years of experience. Relevant research experience in a laboratory setting. Ability to grasp scientific concepts, interpret complex data, and formulate new hypothesis. Competency in standard biochemical lab techniques and the ability to design and carry out complex experiments and interpret data. Demonstrated effectiveness in collaborative projects, and ability to communicate effectively with scientists and management in a highly matrixed organization.

Nice‑to‑Have Practical knowledge and/or experience with bioconjugation, protein purification, analytical biochemistry, scale up, GLP/GMP practices, and technology transfers to manufacturing sites. Team oriented, with excellent oral and written communication skills. Well organized and great attention to detail.

Work Location

Assignment: On Premise

The annual base salary for this position ranges from $68,600.00 to $114,300.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 7.5% of the base salary. Relocation assistance may be available based on business needs and/or eligibility. Candidates must be authorized to be employed in the U.S. by any employer. U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future. Sunshine Act Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, colour, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E‑Verify employer. This position requires permanent work authorization in the United States. Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email [e-mail]. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned. To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI‑use guidelines available on Pfizer Careers.

Benefits

• Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage.
• Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com).
• Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Research and Development

Pfizer careers are like no other. In our culture of individual ownership, we believe in our ability to improve future healthcare, and potential to transform millions of lives. We’re looking for new talent to join our global community, to unearth new innovative therapies that make the world a healthier place.