Senior Associate Scientist, Cellular Genomics

Scorpion Therapeutics; Cambridge (MA); On-site; USD 69,000 - 114,000; Full time

Benefits offered by this job

Health benefits

401(k) plan

Paid time off

Job summary

Scorpion Therapeutics in Cambridge, MA is seeking a genomics data analyst to perform upstream data processing, QC, and troubleshooting of sequencing runs and metadata. You will apply bioinformatics workflows for QC, interpretation, and reproducible reporting, generating QC summaries and figures for integrated genomic readouts.

You will also support experimental design, benchmark new workflows, and execute wet-lab steps as needed, while onboarding others and staying current with single-cell and

Qualifications

• BS with 3+ years relevant experience or MS with 0+ years.
• 1+ year genomics data analysis/QC/visualization/reproducible workflows (bulk/single-cell or spatial/targeted/immune repertoire/epigenomics).
• Python, R, command-line tools, notebooks, version-controlled workflows.

Responsibilities

• Perform upstream data processing, quality assessment, and troubleshooting of sequencing runs, sample metadata, libraries, and genomic datasets.
• Apply computational biology/bioinformatics workflows for QC, biological interpretation, and reproducible reporting.
• Generate and document analytical outputs (QC summaries, exploratory analyses, figures/tables, technical summaries).
• Support experimental design/data needs discussions and contribute to genomic readout interpretation.
• Evaluate/benchmark/qualify new or improved bioinformatic workflows, assays, platforms, and analytical approaches; document results.
• Execute wet-lab component (sample prep, tissue dissociation, cell/nuclei isolation, nucleic acid extraction, library prep/QC, sequencing, data generation).
• Onboard/train others on genomics workflows and documentation best practices.
• Stay current with single-cell genomics, spatial transcriptomics, multiomics, reproducible bioinformatics.
• Draft/maintain analysis and experimental plans, validation reports, work instructions/SOPs; maintain compliant electronic lab notebooks and data integrity.

Skills

Python

R

Command-line

Notebooks

Git

Wet-lab skills

Education

BS with 3+ years experience

MS with 0+ years experience

Tools

Jupyter notebooks

Git

Linux

Job description

Role Responsibilities

• Perform upstream data processing, quality assessment, and troubleshooting of sequencing runs, sample metadata, libraries, and genomic datasets.
• Apply computational biology/bioinformatics workflows (incl. AI-enabled tools as appropriate) for QC, biological interpretation, and reproducible reporting.
• Generate and document analytical outputs (QC summaries, exploratory analyses, figures/tables, technical summaries).
• Support experimental design/data needs discussions and contribute to genomic readout interpretation.
• Evaluate/benchmark/qualify new or improved bioinformatic workflows, assays, platforms, and analytical approaches; document results.
• Execute wet-lab component (sample prep, tissue dissociation, cell/nuclei isolation, nucleic acid extraction, library prep/QC, sequencing, data generation).
• Onboard/train others on genomics workflows and documentation best practices.
• Stay current with single-cell genomics, spatial transcriptomics, multiomics, reproducible bioinformatics.
• Draft/maintain analysis and experimental plans, validation reports, work instructions/SOPs; maintain compliant electronic lab notebooks and data integrity.

Qualifications (Required)

• BS with 3+ years relevant experience OR MS with 0+ years.
• 1+ year genomics data analysis/QC/visualization/reproducible workflows (bulk/single-cell or spatial/targeted/immune repertoire/epigenomics).
• Python, R, command-line tools, notebooks, version-controlled workflows.
• Foundational wet-lab experience (molecular biology/sample or library prep/assay execution).

Preferred

• AI-enabled/agentic bioinformatic tools experience.
• Expertise in inflammation/immunology/neuro-inflammation/translational medicine.

Benefits/Comp (as stated)

• Base salary $68,600-$114,300; bonus target 7.5%; 401(k) and additional retirement contribution; paid time off and health benefits.