Senior Associate Scientist

CHEManager International; Billerica (MA); On-site; USD 90,000 - 136,000; Full time

Benefits offered by this job

Health insurance

Paid time off

Retirement contributions

Job summary

EMD Serono Research and Development Institute in Billerica, MA, is seeking a Senior Associate Scientist to conduct in vitro experiments including cell culture, western blotting and PCR, with overexpression, knockdowns, and CRISPR genome editing to advance target identification.

This lab-based role supports cancer research within a drug discovery setting, requiring hands-on molecular biology skills, strong problem-solving, and collaboration in a cross-functional team.

Qualifications

• Hands-on experience with mammalian cell culture and aseptic technique.
• Experience with genome editing and functional genomics.
• Strong analytical and communication skills.

Responsibilities

• Conduct in vitro experiments including cell culture, western blotting, and PCR.
• Perform overexpression, knockdowns, and CRISPR-based genome editing.
• Contribute to target identification and validation in cancer research.

Skills

Mammalian cell culture

CRISPR genome editing

RNAi

Western blotting

qPCR/TaqMan

Flow cytometry

Cell imaging (Incucyte)

Data analysis

ELNs

Microsoft Office

Genetic engineering

Education

Bachelor's degree in Molecular Biology/Cell Biology/Biochemistry

Master's degree in Molecular Biology/Cell Biology/Biochemistry

Tools

GraphPad Prism

Incucyte live-cell imaging

FACS

PCR instruments

ELN software

Job description

Work Location: Billerica, Massachusetts

Your Role

The EMD Serono Research and Development Institute in Billerica, MA, is hiring a Senior Associate Scientist within our Target Discovery Research group. The Senior Associate Scientist will be responsible for conducting in vitro experiments, including cell culture, western blots, PCR, as well as overexpression, knockdowns, and CRISPR-based genome editing experiments to facilitate target identification and validation. This role offers a laboratory-based opportunity to contribute to the forefront of cancer research within a research-based drug discovery company.

Who You Are

Minimum Qualifications

• Bachelor's degree in Molecular Biology, Cell Biology, Biochemistry, or other Scientific discipline with 2+ years of hands-on laboratory experience, including aseptic techniques for handling mammalian and/or cancer cell lines

OR

• Master's degree in Molecular Biology, Cell Biology, Biochemistry, or other Scientific discipline with 1+ year of hands-on laboratory experience, including aseptic techniques for handling mammalian and/or cancer cell lines

Preferred Qualifications

• Demonstrated proficiency in mammalian cell culture techniques, including routine cell line maintenance, transfection, and isolation of genetically engineered clones
• Ability to operate in a rapidly evolving drug discovery environment, balancing competing priorities while supporting research efforts across diverse target classes, technologies, and therapeutic modalities
• Hands-on experience with functional genomics and gene-editing technologies, including RNA interference (RNAi) and CRISPR-based genome engineering
• Strong expertise in molecular and cellular biology techniques, including western blotting, AlphaLISA, qPCR/TaqMan assays, and related analytical methods
• Experience with flow cytometry (FACS) for cellular phenotyping, transfection assessment, cell sorting, or other cell-based applications
• Experience with cell imaging technologies, including microscopy, Incucyte live-cell imaging, or other high-content imaging platforms
• Excellent analytical, troubleshooting, and problem-solving skills, with the ability to optimize experimental workflows and interpret complex data
• Strong written and verbal communication skills, with a proven ability to collaborate effectively in a cross-functional team environment
• Proficiency with Microsoft Office applications (Word, Excel, and PowerPoint), GraphPad Prism, and electronic laboratory notebooks (ELNs) for data analysis and documentation
• Strong organizational skills and the ability to manage multiple priorities in a fast-paced research environment
• A self-motivated and detail-oriented approach, with a commitment to scientific rigor and high-quality experimental execution

Pay Range for this position: $90,400 - $135,700

The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here.

The Company is an Equal Employment Opportunity employer. No employee or applicant for employment will be discriminated against on the basis of race, color, religion, age, sex, sexual orientation, national origin, ancestry, disability, military or veteran status, genetic information, gender identity, transgender status, marital status, or any other classification protected by applicable federal, state, or local law. This policy of Equal Employment Opportunity applies to all policies and programs relating to recruitment and hiring, promotion, compensation, benefits, discipline, termination, and all other terms and conditions of employment. Any applicant or employee who believes they have been discriminated against by the Company or anyone acting on behalf of the Company must report any concerns to their Human Resources Business Partner, Legal, or Compliance immediately. The Company will not retaliate against any individual because they made a good faith report of discrimination.