Senior Analytical Chemist: HPLC & Method Improvement

BioSpace; Phoenix (AZ); On-site; USD 65,000 - 85,000; Full time

Job summary

Eagle seeks an Analytical Chemist II to perform advanced chemical analyses in a high-volume lab, focusing on HPLC, potency, and impurity testing. You will guide junior staff, maintain data integrity, and support method validation and process improvements.

Ideal candidates hold a Chemistry-related degree with 3–5 years in a regulated lab, and are proficient with HPLC and instrumentation. The role requires strong attention to detail and cross-team collaboration.

Qualifications

• Bachelor’s degree in Chemistry or related field; Master’s preferred.
• 3–5 years in a regulated analytical lab (cGMP, cGLP, ISO 17025, USP, A2LA).
• Experience with sample preparative chemistry and wet chemistry analysis.
• Advanced proficiency with HPLC, UV-Vis and other analytical instrumentation.
• Able to troubleshoot analytical methods and instrumentation independently.
• Experience reviewing laboratory data, quality documentation, and regulatory compliance records.

Responsibilities

• Perform routine and moderately complex chemical analyses, including HPLC, assay, potency, and impurity testing.
• Lead sample tracking, test execution, and result reporting, ensuring accuracy, completeness, and compliance.
• Independently identify, troubleshoot, and resolve unexpected test results or equipment issues.
• Conduct instrument maintenance, calibration, and advanced troubleshooting with minimal supervision.
• Review laboratory SOPs and contribute to their revision or creation; provide guidance to junior staff on SOP compliance.
• Ensure compliance with cGMP, cGLP, ISO 17025, USP, A2LA, and company SOPs.
• Participate in continuous improvement initiatives, method optimization, and high-volume workflow management.
• Train and mentor Analytical Chemist I and entry-level staff.
• Support internal audits, safety inspections, and client audits as needed.
• Assist with special projects, technical evaluations, and cross-functional laboratory initiatives.
• Communicate findings, trends, and recommendations effectively to laboratory and quality leadership.

Skills

HPLC

UV-Vis

Instrumentation

Education

Bachelor's degree in Chemistry

Master's degree preferred

Tools

LIMS

Microsoft Office

Job description

Eagle seeks an Analytical Chemist II to perform advanced chemical analyses in a high-volume lab, focusing on HPLC, potency, and impurity testing. You will guide junior staff, maintain data integrity, and support method validation and process improvements.

Ideal candidates hold a Chemistry-related degree with 3–5 years in a regulated lab, and are proficient with HPLC and instrumentation. The role requires strong attention to detail and cross-team collaboration.