Senior ADC Manufacturing Engineer - Process Transfer

LOTTE Biologics; City of Syracuse (NY); On-site; USD 91,000 - 142,000; Full time

Job summary

LOTTE BIOLOGICS in East Syracuse, NY is seeking a Senior Engineer, ADC Manufacturing. You will lead conjugation, purification, and scale-up across development and production, drive technology transfers and CAPA, and partner with QA, QC, Supply Chain, and Facilities to ensure cGMP compliance.

Ideal candidates hold a BS in a related field, 7+ years in MSAT/Process Engineering, and 2–4 years in ADCs, with hands-on cGMP experience and strong cross-functional collaboration.

Qualifications

• 7+ years in biopharma MSAT, Process Engineering, or Manufacturing Sciences.
• 2-4 years in ADCs or complex bioconjugation preferred.
• Hands-on cGMP experience in clinical or commercial manufacturing.

Responsibilities

• Serve as primary technical authority for ADC conjugation, purification, and formulation.
• Lead technology transfers for First in Human, scale-up, and validation.
• Mentor junior engineers and maintain process descriptions and MBRs.
• Support regulatory filings and audits with technical justification.
• Collaborate with QA, QC, Supply Chain, and Facilities.
• On-the-floor support during batch execution.
• Lead CAPA investigations for OOS/OOT and deviations.
• Assess process performance with DOE and multivariate analysis.

Skills

Leadership

Cross-functional teamwork

Technical writing

Problem solving

On-floor support

Education

Bachelor's degree in Chemical Engineering

MS/PhD preferred

Tools

JMP

DOE

Job description

LOTTE BIOLOGICS in East Syracuse, NY is seeking a Senior Engineer, ADC Manufacturing. You will lead conjugation, purification, and scale-up across development and production, drive technology transfers and CAPA, and partner with QA, QC, Supply Chain, and Facilities to ensure cGMP compliance.

Ideal candidates hold a BS in a related field, 7+ years in MSAT/Process Engineering, and 2–4 years in ADCs, with hands-on cGMP experience and strong cross-functional collaboration.