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Portal Biotechnologies, headquartered in Watertown, MA, is a rapidly scaling cell-engineering platform company with three high-value lines spanning biopharma R&D screening, cell therapy manufacturing, and AI training data generation. The role seeks a PhD-level scientist who will deploy Portal’s platform with customers, building trusted relationships and collaborating with industry and academic partners.
The ideal candidate has an extroverted, entrepreneurial mindset, a passion for scientific
Portal Biotechnologies, headquartered in Watertown, MA, is a rapidly scaling cell-engineering platform company operating across three high-value business lines (biopharma R&D screening, next-generation cell therapy manufacturing, and AI training data generation), addressing markets totaling $100B+. Since launching its first product in 2024, Portal has built a network of 100+ active customers, including the top 10 global pharmaceutical companies and leading academic hospitals and cancer centers worldwide.
Backed by $15M in venture funding and an $8M DARPA contract, Portal’s proprietary mechanoporation technology enables efficient multiplex delivery of diverse cargos such as RNA, proteins, small molecules, and gene-editing tools without compromising cell function. The approach is simple and scalable, supporting applications from high-throughput drug screening to clinical-scale manufacturing, and it works both as a stand-alone system and as an integrated component in third-party platforms.
In biopharma R&D, Portal’s products enable novel screening assays by delivering otherwise cell-impermeable probes and candidate molecules directly into live cells, unlocking intracellular access that standard methods cannot provide. In cell therapy, Portal’s GMP-integrated consumables and a DARPA-funded portable device (launching 2027) are aimed at making engineered cell therapies as accessible and ubiquitous as an infusion pump. In AI training data, Portal generates high-value, multiparametric datasets from primary cells, producing biologically relevant training data that current cell line-based methods cannot replicate.
With a leadership team bringing decades of experience in biotech operations and clinical cell therapy development, Portal is positioned to become the foundational platform for next-generation cell engineering, drug discovery, and biological AI data generation.
We are seeking a PhD-level scientist who enjoys applying their scientific expertise beyond the bench while remaining deeply connected to cutting-edge science and technology. In this role, you’ll be instrumental in deploying Portal’s platform with customers and partner organizations by building trusted relationships and collaborating with a diverse mix of industry and academic professionals.
The ideal candidate brings an extroverted, entrepreneurial mindset, a passion for scientific innovation, and the ability to thrive in a fast-paced, goal-oriented environment. This role sits at the intersection of science, strategy, and sales - perfect for someone who enjoys translating complex biology into real-world impact.
Portal’s headquarters are located in Watertown, MA with free on-site parking. We also have an additional site in San Carlos, CA. On-site parking is available and it's a 15 minute walk from the Caltrain station. We are open to hiring for either location.
In compliance with federal law, all persons hired will be required to verify identity and eligibility to work in the United States and to complete the required employment eligibility verification form upon hire.
We are proud to be an equal opportunity employer and to provide equal opportunities to all employees and applicants for employment without regard to race, color, religion, sex or gender identity, national origin, age, sexual orientation, disability, or genetics. In addition to federal law requirements, we comply with applicable state and local laws governing nondiscrimination in employment.