Scientist, Quantitative Bioanalytics - Analytical and Biological Mass Spectrometry (ABMS)

Regeneron; Village of Tarrytown (NY); On-site; USD 110,000 - 150,000; Full time

Job summary

Regeneron Pharmaceuticals, Inc. in Tarrytown, NY seeks a Scientist to join the Quantitative Bioanalytics (QBA) team.

You will develop, qualify, and apply LC-MS-based bioanalytical assays to support R&D programs, working closely with cross-functional teams and contributing to state-of-the-art mass spectrometry analyses. The role offers opportunities to advance bioanalytical technologies and to contribute to biologics characterization while maintaining rigorous data quality and documentation

Qualifications

• BS or MS in Chemistry, Biochemistry, Analytical Chemistry, Pharmaceutical Sciences, or related field.
• 6+ years (MS) or 8+ years (BS) of industrial or academic experience with LC-MS based bioanalytical assays.

Responsibilities

• Develop, qualify, and validate LC-MS-based bioanalytical assays for biotherapeutics and biomarkers.
• Provide bioanalytical support across research, preclinical, clinical, and biodistribution studies.
• Tackle method troubleshooting and ensure data quality and scientific integrity.

Skills

LC-MS workflows

Bioanalysis

Method development

Data analysis

Cross-functional collaboration

Education

BS in Chemistry

MS in Analytical Chemistry

Tools

Triple Quadrupole

Q-TOF

Orbitrap

Job description

Scientist, Quantitative Bioanalytics - Analytical and Biological Mass Spectrometry (ABMS)

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a highly motivated and collaborative Scientist to join the Quantitative Bioanalytics (QBA) team within the Analytical and Biological Mass Spectrometry (ABMS) Group. In this exciting role, you will work in a pioneering, state-of-the-art mass spectrometry laboratory to develop, qualify, and apply LC-MS-based bioanalytical assays and other analytical methods to support R&D programs. You will have opportunities to contribute to innovative mass spectrometry technologies applied to bioanalysis and biologics characterization across Regeneron’s diverse and evolving therapeutic pipeline, while collaborating closely with cross-functional teams to understand bioanalytical needs, coordinate samples and study activities, and align priorities and timelines.

This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

When & where:

• Shift Requirements: Full-time
• Location: On-site in Tarrytown, NY

Discover your role:

• Perform LC-MS-based assay development, qualification, and validation for biotherapeutics and biomarkers in biological matrices to support Regeneron’s R&D pipelines
• Perform bioanalysis and provide bioanalytical support for research, preclinical, clinical, and biodistribution studies by quantifying therapeutics or biomarkers in biological study samples, with increasing independence and project ownership
• Apply state-of-the-art LC-MS (e.g., triple quadrupole, Q-TOF, and Orbitrap) coupled with manual or automated sample preparation (e.g., liquid handlers and other automation robots) to investigate biotherapeutics, including antibodies, antibody-drug conjugates (ADCs), antibody-oligonucleotide conjugates (AOCs), antibody-tethered ligands (ATLs), adeno-associated viruses (AAVs), peptides, and other novel modalities
• Troubleshoot and optimize methods, and ensure data quality and scientific integrity of bioanalytical and biologics characterization results, to support data-driven decisions
• Maintain accurate and reliable records, including electronic lab notebooks (ELNs) and other pertinent documentation; analyze and interpret results; and effectively communicate findings at team and cross-functional meetings, and in technical reports, regulatory documents, conferences, and peer-reviewed publications
• Work in a laboratory-based role with strong support for skill and career development, while taking increasing ownership of projects and priorities
• Develop and troubleshoot analytical methods, solve scientific and technical problems, and explore new technologies and approaches to address bioanalytical challenges
• Demonstrate excellent attention to detail, good record keeping, and organizational skills
• Work independently and collaboratively across teams, build productive working relationships, and coordinate samples, activities, priorities, timelines, and deliverables across multiple programs
• Think and act independently on well-defined projects, while working collaboratively in a team environment and adapting to changing priorities
• Communicate clearly and effectively, with excellent verbal and written communication skills
• Be results-driven, adaptable, and scientifically curious, with the ability to thrive in an innovative, fast-paced R&D environment

This role requires:

• BS or MS in Chemistry, Biochemistry, Analytical Chemistry, Pharmaceutical Sciences, or a related field
• 6+ years (MS) or 8+ years (BS) of industrial or academic experience with LC-MS based bioanalytical assays for biomarkers, protein therapeutics, antibodies, AAVs, or other therapeutic modalities
• Hands-on experience with LC-MS and advanced mass spectrometry platforms, such as triple quadrupole, Q-TOF, and Orbitrap, with a strong understanding of mass spectrometry techniques and their applications to large-molecule analysis
• Experience with GxP laboratory environment, documentation, and regulatory compliance in the biotech or biopharmaceutical industry is a plus
• Deep understanding of analytical method qualification and validation is highly desired; knowledge of ELISA and other ligand-binding assays is a plus

We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process.

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on-site. Please speak with your recruiter and hiring manager for more information about on-site expectations for your role and location.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

• Location: Tarrytown, United States of America
• Location: Tarrytown, United States of America
• Location: Tarrytown, United States of America

We take hiring seriously - because finding the right person for our mission matters as much to us as finding the right company matters to you. Our process is thorough by design: we want every new hire to feel confident they've found a place where their work truly matters, and we want to be just as confident we've found someone who'll thrive here. It's a two-way conversation, not a one-way interview.

Part of the team

Where You'll Make an Impact

Here, you’ll collaborate with teams across regions to help move our mission forward.

We invest in your health and stability so you can focus on making meaningful impact. Below is a highlight of benefit programs that may be available to you, depending on your country of employment, role, etc.