Scientist, Quantitative Bioanalytics - Analytical and Biological Mass Spectrometry (ABMS)

Regeneron Pharmaceuticals, Inc (USA); Village of Tarrytown (NY); On-site; USD 94,000 - 153,000; Full time

Benefits offered by this job

Annual bonuses

401(k) company match

Health and wellness programs

Paid time off

Job summary

Regeneron Pharmaceuticals, Inc (USA) seeks a Scientist to join the Quantitative Bioanalytics team in the ABMS Group. You will develop and qualify LC-MS-based bioanalytical assays and support R&D programs, collaborating with cross-functional teams to deliver high-quality data and insights.

The role involves state-of-the-art LC-MS platforms, ELISA and other ligand-binding methods, and opportunities to advance bioanalytical technologies within a fast-paced R&D environment. On-site in Tarrytown, NY.

Qualifications

• BS or MS in Chemistry, Biochemistry, Analytical Chemistry, Pharmaceutical Sciences, or a related field.
• Hands-on LC-MS with multiple platforms (e.g., triple quadrupole, Q-TOF, Orbitrap).
• Experience in regulated biotech/biopharmaceutical environments and method qualification/validation desirable.

Responsibilities

• Perform LC-MS-based assay development, qualification, and validation for biotherapeutics and biomarkers in biological matrices.
• Bioanalysis support for research, preclinical, clinical, and biodistribution studies with increasing independence.
• Troubleshoot and optimize methods; ensure data quality and scientific integrity; communicate findings in reports and meetings.

Education

BS or MS in Chemistry, Biochemistry, Analytical Chemistry, Pharmaceutical Sciences, or a related field

Tools

LC-MS

Q-TOF

Orbitrap

ELISA

Job description

Build our future together: At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a highly motivated and collaborative Scientist to join the Quantitative Bioanalytics (QBA) team within the Analytical and Biological Mass Spectrometry (ABMS) Group. In this exciting role, you will work in a pioneering, state-of-the-art mass spectrometry laboratory to develop, qualify, and apply LC-MS-based bioanalytical assays and other analytical methods to support R&D programs. You will have opportunities to contribute to innovative mass spectrometry technologies applied to bioanalysis and biologics characterization across Regeneron’s diverse and evolving therapeutic pipeline, while collaborating closely with cross-functional teams to understand bioanalytical needs, coordinate samples and study activities, and align priorities and timelines. This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

Shift Requirements

Full-time

On-site in Tarrytown, NY

Discover Your Role

• Perform LC-MS-based assay development, qualification, and validation for biotherapeutics and biomarkers in biological matrices to support Regeneron’s R&D pipelines
• Perform bioanalysis and provide bioanalytical support for research, preclinical, clinical, and biodistribution studies by quantifying therapeutics or biomarkers in biological study samples, with increasing independence and project ownership
• Apply state-of-the‑art LC‑MS (e.g., triple quadrupole, Q‑TOF, and Orbitrap) coupled with manual or automated sample preparation (e.g., liquid handlers and other automation robots) to investigate biotherapeutics, including antibodies, antibody‑drug conjugates (ADCs), antibody‑oligonucleotide conjugates (AOCs), antibody‑tethered ligands (ATLs), adeno‑associated viruses (AAVs), peptides, and other novel modalities
• Troubleshoot and optimize methods, and ensure data quality and scientific integrity of bioanalytical and biologics characterization results, to support data‑driven decisions
• Maintain accurate and reliable records, including electronic lab notebooks (ELNs) and other pertinent documentation; analyze and interpret results; and effectively communicate findings at team and cross‑functional meetings, and in technical reports, regulatory documents, conferences, and peer‑reviewed publications
• Work in a laboratory‑based role with strong support for skill and career development, while taking increasing ownership of projects and priorities
• Develop and troubleshoot analytical methods, solve scientific and technical problems, and explore new technologies and approaches to address bioanalytical challenges
• Demonstrate excellent attention to detail, good record keeping, and organizational skills
• Work independently and collaboratively across teams, build productive working relationships, and coordinate samples, activities, priorities, timelines, and deliverables across multiple programs
• Think and act independently on well‑defined projects, while working collaboratively in a team environment and adapting to changing priorities
• Communicate clearly and effectively, with excellent verbal and written communication skills
• Be results‑driven, adaptable, and scientifically curious, with the ability to thrive in an innovative, fast‑paced R&D environment

This Role Requires

• BS or MS in Chemistry, Biochemistry, Analytical Chemistry, Pharmaceutical Sciences, or a related field
• 6+ years (MS) or 8+ years (BS) of industrial or academic experience with LC-MS based bioanalytical assays for biomarkers, protein therapeutics, antibodies, AAVs, or other therapeutic modalities
• Hands‑on experience with LC-MS and advanced mass spectrometry platforms, such as triple quadrupole, Q‑TOF, and Orbitrap, with a strong understanding of mass spectrometry techniques and their applications to large‑molecule analysis
• Experience with GxP laboratory environment, documentation, and regulatory compliance in the biotech or biopharmaceutical industry is a plus
• Deep understanding of analytical method qualification and validation is highly desired; knowledge of ELISA and other ligand‑binding assays is a plus

Salary Range (annually) $93,900.00 - $153,300.00

Benefits

Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role:

• annual bonuses or other incentive plans
• equity awards
• pension or retirement benefits
• 401(k) company match
• health and wellness programs
• fitness centers
• insurance benefits (e.g. medical, dental, vision, life and disability)
• paid time off
• family support benefits

We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship. Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

For other locations, additional information will be provided during the recruitment process.

Regeneron is a leading biotechnology company that invents life‑transforming medicines for people with serious diseases. Founded and led for over 30 years by physician‑scientists, our unique ability to repeatedly and consistently translate science into medicine has led to nine FDA‑approved treatments and numerous product candidates in development, almost all of which were homegrown in our laboratories. Our medicines and pipeline are designed to help patients with eye diseases, allergic and inflammatory diseases, cancer, cardiovascular and metabolic diseases, neurology, infectious diseases and rare diseases. Regeneron is also proud of award‑winning culture of innovation, being recognized as a Great Place to Work in 2021, Fast Company’s Best Workplace for Innovators in 2020, and Forbes JUST companies in 2020, among others.