Scientist, Probe Design

Advanced Cell Diagnostics, Inc.; Newark (CA); On-site; USD 89,300 - 146,900; Full time

Benefits offered by this job

Medical, dental, and vision insurance

401k plan

Tuition reimbursement

Paid parental leave

Job summary

Advanced Cell Diagnostics, Inc. seeks a Scientist, Probe Design to join its R&D team in Newark, California. This role involves designing and optimizing RNAscope probes, providing technical support, and collaborating with commercial teams.

The ideal candidate holds a PhD and has extensive research experience in molecular biology and bioinformatics. Salary ranges between $89,300 and $146,900, with comprehensive benefits and opportunities for career development.

Qualifications

• PhD with 4+ years of research experience in molecular biology or similar.
• In-depth knowledge of genes and RNA biology.
• Experience with programming languages like Python and R.

Responsibilities

• Design and optimize RNAscope probes using specialized software.
• Provide technical support and training for probe products.
• Collaborate with R&D for new product development.

Skills

Molecular biology

Bioinformatics

Linux

Python

Research experience

Education

PhD in relevant field

Tools

BLAST/BLAT

Next-generation sequencing tools

Job description

By joining Bio-Techne, you’ll join a company with a powerful and positive purpose of enabling cutting‑edge research in Life Sciences and Clinical Diagnostics. Bio-Techne, and all of its brands, provides tools for researchers to further treat and prevent disease worldwide. Pay Range: $89,300.00 - $146,900.00

Advanced Cell Diagnostics, Inc. (ACD) is a leader in the field of molecular pathology and tissue-based diagnostics. Our core RNAscope® technology is the world’s first multiplex fluorescent and chromogenic in situ hybridization platform capable of detecting and quantifying RNA biomarkers in situ at single molecule sensitivity. RNAscope® is an ideal platform for developing the next generation of tissue-based companion diagnostics. We are committed to continued innovation to bridge the gap between basic research and clinical medicine to fulfill the promise of personalized medicine.

The Scientist, Probe Design is a key member of the R&D team. The Scientist will work within a highly dynamic group to develop and optimize new probe products based on our RNAscope® technology and work closely with our commercial team to identify and support customer needs.

Responsibilities

• Design made‑to‑order RNAscope probes for target sequences using proprietary software
• Answer technical inquiries related to design of target probes & submission of New Probe Requests (NPR)
• Review NPR forms for accurate and efficient probe designs
• Utilize Linux command‑line tools for sequence alignments (BLAST/BLAT), probe selection, specificity
• Provide probe product training and troubleshooting for Advanced Cell Diagnostics scientific probe product lines via phone and email
• Act as primary contact for customers regarding technical issues, as well as providing scientific consultation for research use only inquiries
• Collaborate with Commercial and Marketing teams to meet the needs of customers
• Ensure customer service excellence and guaranteed response times by actively monitoring SalesForce queue, inbox, phone calls, and ensuring all issues are resolved in a timely and comprehensive manner
• Contribute to ongoing new product development and introduction with R&D teams in a laboratory environment
• Contribute to the ongoing development of the Probe Design team's knowledgebase
• Present scientific and product updates to customers and internal teams

Qualifications

• PhD with 4+ years of research experience in molecular biology, bioinformatics, computational biology or a closely related field
• In‑depth knowledge of genes and sequences, RNA biology
• Familiarity with standard bioinformatics tools (Python, R, or equivalent), and a programming language (C/C++, Java)
• Experience in commonly used biological databases and bioinformatics software tools
• Ability to work within a multidisciplinary team of computational biologists, molecular biologists, imaging software scientists, biochemists and others
• Post‑graduate experience with experimental design, cell and molecular techniques
• Very adept at diagnosing, troubleshooting and solving complex technical problems with a variety of biological assays
• Highly self‑directed, conscientious, articulate, and possesses excellent presentation and teaching skills
• Experience: 2+ years in Biotech/Biopharma R&D; 2+ years with Linux, Python, Perl or other programming languages; 2+ years with next‑generation sequencing platforms or sequencing tools; prior experience in probe design across multiple species; experience in biological sequence analysis tasks such as database searches and multiple sequence alignment tools
• Committed to total customer satisfaction with outstanding interpersonal skills and professionalism
• Customer‑facing experience with a strong scientific capacity

Working Conditions

Ability to travel ~10% of time. Work performed in office settings. Regular use of computers. Work may occasionally require extended hours to meet project deadlines.

Physical Requirements

Prolonged periods of sitting or standing at a computer.

Benefits

We offer competitive insurance benefits starting on day one: medical, dental, vision, life, short‑term disability, long‑term disability, pet, and legal and ID shield. We invest in our employees’ financial futures through 401k plans, an employee stock purchase plan (ESPP), Health Saving Account (HSA), Flexible Spending Account (FSA), and Dependent Care FSA. We empower our employees to develop their careers through mentorship, promotional opportunities, training and development, tuition reimbursement, internship programs, and more. We offer employee resource groups, volunteer paid time off, employee events, and charity drives to build a culture of caring and belonging. We offer an accrued leave policy with paid holidays, paid time off, and paid parental leave. We foster a culture of empowerment and innovation, where employees feel valued and encouraged to bring their new ideas to the table.

Equal Employment Opportunity (EEO) Statement

Bio-Techne is an E-Verify Employer in the United States. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.